The Journal of Investigational Allergology and Clinical Immunology (J Investig Allergol Clin Immunol) provides an attractive and very active forum for basic and clinical research in allergology and clinical immunology. The journal publishes original works, reviews, short communications and opinions. It is the Official Journal ofthe Spanish Society of Allergology and Clinical Immunology (SEAIC). The journal will appear bimonthly (6 issues each year). The peer-review system, based on a team of internationally renowned and committed editors, guarantees the scientific quality of the papers.

Current ISSUE

2019; volume 29, Issue 4
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Autoimmune Aspects of Kawasaki Disease
Sakurai Y
[summary] [PDF full-Text]

Obesity and Asthma: Key Clinical Questions
Garcia-Rio F, Alvarez-Puebla MJ, Esteban-Gorgojo I, Barranco P, Olaguibel JM
[summary] [PDF full-Text]

Original Articles

Quality Standards for Allergen Immunotherapy Clinics in Spain: Consensus Document
Tabar AI, Núñez Acevedo B, Beitia Mazuecos JM, Fernández Ibáñez E, Garde Garde J, Hernández Fernández de Rojas D, De Luque Piñana V, Ojeda Fernández P, Reaño Martos M, Rodríguez Fernández F, Roger Reig A, Andrés Martínez J, Moreno Aguilar C, Vidal C
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Heterogeneous Predisposing Factors and Etiology of Edema of the Uvula in a Spanish Population
Barbarroja-Escudero J, Asúnsolo-Del-Barco A, Sánchez-González MJ, Rodríguez-Rodríguez M, Alvarez-Mon M
[summary] [PDF full-Text]

Quantitative, Absolute Count–Based T-Cell Analysis of CD69 Upregulation as a New Methodology for In Vitro Diagnosis of Delayed-Type Hypersensitivity Reaction to Nickel
Koren A, Silar M, Rupnik H, Zidarn M, Korosec P
[summary] [PDF full-Text] [Supplemental Materials]

Practitioner’s Corner

Oral Immunotherapy to Hake in 8 Pediatric Patients
Martorell-Calatayud C, Carnés J, Michavila Gómez A, Dopazo Fernández L, Echeverría Zudaire L, Santana Rodríguez C, Gómez Galán C, Toral Pérez T, Rodríguez Del Río P, Martorell Aragonés A
[summary] [PDF full-Text] [Supplemental Materials]

Allergic Rhinoconjunctivitis Due to Pediculus humanus capitis
de las Marinas Alvarez MD, Martorell Calatayud C, Castillo Fernandez M, Alvariño Martín M, Félix Toledo R, Cerdá Mir JC, Pineda de la Losa F, Martorell Aragonés A
[summary] [PDF full-Text]

Anaphylaxis Related to Passive Second-Hand Exposure to Cannabis sativa Cigarette Smoke in Adolescents
Cabrera-Freitag P, Infante S, Bartolomé B, Álvarez-Perea A, Fuentes-Aparicio V, Zapatero Remón L
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Severe Maculopapular Exanthema Induced by Regorafenib: Successful Desensitization and Adaptation of a Dosage Regimen
García-Gutiérrez I, Acevedo M, Tornero P, Matilla A, Márquez L, Sánchez-Herrero A, Prieto-García A
[summary] [PDF full-Text] [Supplemental Materials]

Reactions to Shrimp Including Severe Anaphylaxis in Mite- and Cockroach-Allergic Patients Who Have Never Eaten Shrimp: Clinical Significance of IgE Cross-Reactivity to Tropomyosins From Different Sources
Martins TF, Mendonça TN, Melo JML, Moreno AS, Januário YC, DaSilva LLP, Dias MM, Meireles PR, Santos KS, Yang AC, Arruda LK
[summary] [PDF full-Text] [Supplemental Materials]

Angioedema-Induced by Nonsteroidal Anti-inflammatory Drugs: A Genotype-Phenotype Correlation in A Brazilian Population
Ensina LF, Martin RP, Filippelli-Silva R, Veronez CL, Sole D, Pesquero JB
[summary] [PDF full-Text] [Supplemental Materials]

The Lymphocyte Transformation Test Is Useful in the Diagnosis of Fixed Drug Eruption Induced by Etoricoxib
Movsisyan M, Fiandor A, González-Muñoz M, Quirce S, Bellón T, Hakobyan A, Marques-Mejias MA, Domínguez-Ortega J, Cabañas R
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Delayed Hypersensitivity Reaction to Lenalidomide: 2 Different Clinical Patterns in the Same Patient
Noguerado-Mellado B, Rojas-Pérez-Ezquerra PD, Tornero Molina P, Ballesteros M, Zubeldia Ortuño JM
[summary] [PDF full-Text]

Anaphylaxis to Clavulanic Acid: A 7-Year Survey
Silveira AM, Gaspar Â, Benito-Garcia F, Couto S, Matias J, Chambel M, Morais-Almeida M
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Der p 23: Clinical Relevance of Molecular Monosensitization in House Dust Mite Allergy
Matos Semedo F, Dorofeeva Y, Pires AP, Tomaz E, Taborda Barata L, Inácio F, Valenta R
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Occupational Asthma Caused by Powder Paint in the Automotive Industry
Tiotiu A, Thaon I, Poussel M, Penven E
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Usefulness of Omalizumab and Sting Challenge Test in Hymenoptera Venom Allergy and Mastocytosis
González-de-Olano D, Padial-Vilchez MA, Núñez-Acevedo B, de-Calzada-Bustingorri MP, de-Andrés-Martín A, Caldas C, Piris-Villaespesa M, de-la-Hoz-Caballer B
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Recurrent Drug-Induced Liver Injury With Cetirizine and Amoxicillin–Clavulanate Potassium
Vilà-Nadal G, Lleonart Bellfill R, Martí Garrido J, Baliellas Comellas C, Corominas Sánchez M
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Impact of Low Dose Chlorine Inhalation in Healthy Humans: A Pilot Study
Ojanguren I, Chaboillez S, Cloutier Y, Panariti A, McGovern TK, Martin JG, Lemiere C
[summary] [PDF full-Text] [Supplemental Materials]

Selection of Biologics in Severe Asthma: A Multifaceted Algorithm
Dávila I, Quirce S, Olaguibel JM
[summary] [PDF full-Text] [Supplemental Materials]

Desensitization to Filgrastim in a 2-Year-Old Girl With a Vaginal Endodermal Sinus Tumor
González-Cavero L, Gómez-Traseira C, Fiandor A, Entrala A, Quirce S
[summary] [PDF full-Text]

A Rare Case of Plastic Bronchitis Following Bronchial Thermoplasty
Barbarroja-Escudero J, Sánchez-González MJ, Ruíz-Peña A, Pérez-Labour RA, Rodríguez-Rodríguez M, Alvarez-Mon M
[summary] [PDF full-Text] [Supplemental Materials]

Letters to the Editor

“Too Many Cooks Spoil the Broth”: The More Antigens Present, the Easier, the Quicker, and the More Severe the Anaphylaxis
Kounis NG, Koniari I, Velissaris D, Plotas P, Tsigkas G, Soufras GD, Chourdakis E, Davlouros P, Hahalis G
[summary] [PDF full-Text]

Responses to Biological Therapy in Severe Eosinophilic Asthma
Alvarez-Puebla MJ, Arroabarren E, Zavala MJ, Corcuera A, Olaguibel A, Olaguibel JM
[summary] [PDF full-Text]