The Journal of Investigational Allergology and Clinical Immunology (J Investig Allergol Clin Immunol) provides an attractive and very active forum for basic and clinical research in allergology and clinical immunology. The journal publishes original works, reviews, short communications and opinions. It is the Official Journal ofthe Spanish Society of Allergology and Clinical Immunology (SEAIC). The journal will appear bimonthly (6 issues each year). The peer-review system, based on a team of internationally renowned and committed editors, guarantees the scientific quality of the papers.

Current ISSUE


2025; volume 35, Issue 4
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Review

Climate Change–Associated Environmental Factors and Pollutants: Impact on Allergic Diseases, Epidemiology, Severity, and Health Care Burden
Montoro J, Antolín-Amérigo D, Izquierdo-Domínguez A, Zapata JJ, García-Gallardo MV, González R, Armentia A, Rondón C, Fernández MM, Pedrero SG, Valero A
[summary] [PDF full-Text] [Supplemental Materials]

Perspectives in the Molecular Mechanisms Underlying Anaphylaxis
Esteban V, Skrabski F, Perales-Chorda C, Puente-Crespo Y, Muñoz-Cano R, Cardona V, Anaphylaxis Committee of the Spanish Society of Allergy and Immunology (SEAIC)
[summary] [PDF full-Text]

Original Articles

Pharmacokinetics and Safety of Bilastine 10 mg/d in Children Aged 2 to 5 Years With Allergic Rhinoconjunctivitis or Urticaria: A Phase 3 Clinical Trial
Majorek-Olechowska B, Slomskis T, Zollerová L, Martín I, Sánchez C, Gilaberte I, Arranz P, BILA-4021/PED Research Group
[summary] [PDF full-Text] [Supplemental Materials]

Fecal IgE Analyses Reveal a Role for Stratifying Peanut-Allergic Patients
Czolk R, Codreanu-Morel F, de Nies L, Busi SB, Halder R, Hunewald O, Boehm TM, Hefeng FQ, De Beaufort C, Wilmes P, Ollert M, Kuehn A
[summary] [PDF full-Text] [Supplemental Materials]

Longitudinal Follow-up Reveals Peripheral Immunological Changes Upon Tick Bite in α-Gal–Sensitized Individuals
Swiontek K, Fischer J, Hedin F, Revets D, Riel S, Chakrapani N, Mackenstedt U, Biedermann T, Kuehn A, Cosma A, Ollert M, Hilger C
[summary] [PDF full-Text] [Supplemental Materials]

Practitioner's Corner

Short Communications

Reduced Prostaglandin D2 Production by Airway Fibroblasts in Nonsteroidal Anti-inflammatory Drug- Exacerbated Airway Disease
Roca-Ferrer J, Machado-Carvalho L, Picado C
[summary] [PDF full-Text] [Supplemental Materials]

Prioritization of Children With Anaphylaxis in Pediatric Emergency Departments: Results of a National Survey From Spain
Arroabarren Aleman E, de Vicente Jimenez TM, Alvarez García O, Baynova K, Candón Morillo R, Reche Frutos M, Pediatric Allergy Committee of the Spanish Allergology and Clinical Immunology Society (Comité de Alergia Infantil. Sociedad Española de Alergología e Inmunología Clínica)
[summary] [PDF full-Text] [Supplemental Materials]

Obese Asthma Syndrome: Multiple Inflammatory Patterns and A Key Solution
Bantulà M, García A, Picado C, Arismendi E
[summary] [PDF full-Text] [Supplemental Materials]

Code Anaphylaxis: Enhancing the Management of Hymenoptera Venom Anaphylaxis
Santana M, Armisén M, Feás X, Vidal C
[summary] [PDF full-Text]

Sensitization to Pru p 7 in Peach-Allergic Patients Sensitized to Pru p 3 in Areas of High Exposure to Cypress Pollen
Tomás-Pérez M, Vera-Berrios RN, Casas-Saucedo R, Galleani C, González-Bravo L, Gonzalo-Fernández A, González-Pérez A, Rodríguez-Mazariego E, Ruano-Zaragoza M, Zambrano-Ibarra G, Bartra-Tomás J
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Case Reports

Successful Desensitization to Ramucirumab in Signet Cell Gastric Adenocarcinoma
Villarreal-González RV, Madrazo-Morales M, Sáenz- Cantú KS, García Rosas C, Burguete-Torres A, Vidal- Gutiérrez O
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A Case of Strongyloidiasis Mimicking a Drug Hypersensitivity Reaction to Imatinib
El Rhermoul FZ, Slater S, Madrigal-Burgaleta R
[summary] [PDF full-Text]

Catalase: A New Potential Allergen in Hypersensitivity to Avocado
Gómez-Fariñas C, Sánchez-Sánchez S, Pineda de La Losa F, López Rico MR, Parra Arrondo A, García-Paz V
[summary] [PDF full-Text]

Egg Oral Immunotherapy With Dupilumab Premedication in an Adult Patient
Lopez-Raigada A, Fatou R, Fernandez-Perez C, Gutiérrez- Fernandez D, Vega F
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Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Induced by Meropenem in a Patient Receiving Avelumab and Subsequent Flare-Up
Aulenbacher J, Mockenhaupt M, Biedermann T, Brockow K
[summary] [PDF full-Text] [Supplemental Materials]

Letters to the Editor

Cytokine Release Reaction After Subcutaneous Daratumumab: Possible Relationship With Hymenoptera Allergy
Torres Górriz MC, Borrás Cuartero J, Valls Ten T, Beltrán Agost S, Enrique E
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