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Review

Response to monoclonal antibodies in asthma: definitions, potential reasons for failure and therapeutic options for suboptimal response
Pérez de Llano L, Cisneros C, Domínguez-Ortega J, Martínez-Moragón E, Olaguibel JM, Plaza V, Quirce S, Dávila I
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0857
[summary] [PDF full-Text]

Severe asthma and biologics: managing complex patients
Matucci A, Micheletto C, Vultaggio A
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0856
[summary] [PDF full-Text]

Asthma exacerbations: the genes behind the scenes
Herrera-Luis E, Forno E, Celedón JC, Pino-Yanes M
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0878
[summary] [PDF full-Text]

The impact of inhalers for asthma on the global climate: a systematic review of carbon footprint and clinical outcomes in Spain
Montoro J, Antolín-Amérigo D, Izquierdo-Domínguez A, Zapata JJ, González G, Valero A
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0887
[summary] [PDF full-Text] [Supplemental Materials]

Expert review and consensus on the t2t management of hereditary angioedema: from the scientific evidence to clinical practice
Caballero T, Lleonart-Bellfill R, Pedrosa M, Ferrer L, Guilarte M
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0875
[summary] [PDF full-Text]

Guidelines

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC)
Paño-Pardo JR, Moreno Rodilla E, Cobo Sacristan S, Cubero Saldaña JL, Periañez Párraga L, del Pozo León JL, Retamar-Gentil P, Rodríguez Oviedo A, Torres Jaén MJ, Vidal-Cortes P, Colás Sanz C
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0859
[summary] [PDF full-Text] [Supplemental Materials]

Original Articles

Clinical and immunological characterization of perilla seed allergy in children
Jeong K, Lee SY, Jeon SA, Gantulga P, Nam JY, Hong SJ, Lee S
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0756
[summary] [PDF full-Text] [Supplemental Materials]

Sex differences in baseline risk factors for the incidence of asthma between early adolescence and young adulthood
Kalm-Stephens P, Nordvall L, Janson C, Malinovschi A, Alving K
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0763
[summary] [PDF full-Text] [Supplemental Materials]

Systemic Corticosteroids in Patients with Bronchial Asthma: A Real-Life Study
Izquierdo JL, Almonacid C, Campos C, Morena D, Benavent M, González-de-Olano D, Rodríguez JM
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0765
[summary] [PDF full-Text] [Supplemental Materials]

Economic consequences of the overuse of short-acting beta-adrenergic agonists (SABA) in the treatment of asthma in Spain
Valero A, Molina J, Nuevo J, Simon S, Capel M, Sicras-Mainar A, Sicras-Navarro A, Plaza V
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0767
[summary] [PDF full-Text] [Supplemental Materials]

Atopic manifestations are underestimated clinical features in various primary immunodeficiency disease phenotypes
de Wit J, Dalm V, Totté JEE, Kamphuis LSJ, Vermont CL, van Osnabrugge FY, van Hagen PM, Pasmans SGMA
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0768
[summary] [PDF full-Text] [Supplemental Materials]

Asthma mortality in Spain from 1980 to 2019. Trends and perspectives in new treatment era
Delgado-Romero J, Pereyra-Rodriguez JJ
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0771
[summary] [PDF full-Text] [Supplemental Materials]

A prospective study of costs associated with the evaluation of allergic reactions to radiological contrast media
Sobrino-García M, Muñoz-Bellido FJ, Moreno E, Gracia-Bara MT, Laffond E, Lázaro-Sastre M, Martín-García C, Dávila I
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0774
[summary] [PDF full-Text] [Supplemental Materials]

Transition of adolescents with severe asthma from pediatric to adult care in Spain: the STAR consensus
Valverde-Molina J, Fernández-Nieto M, Torres-Borrego J, Lozano Blasco J, de Mir-Messa I, Blanco-Aparicio M, Nieto A, Figuerola Mulet J, Moure AL, Sánchez-Herrero MG, Sánchez-García S
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0780
[summary] [PDF full-Text] [Supplemental Materials]

Comparison of intact allergen extracts and allergoids for subcutaneous immunotherapy - the effect of chemical modification differs both between species and between individual allergen molecules
Henmar H, Nedergaard Larsen J, Lund L, Hvalsøe Meno K, Ferreras M
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0783
[summary] [PDF full-Text]

Immunologic heterogeneity in two Cartilage-Hair Hypoplasia (CHH) patients with distinct clinical course
Gamliel A, Nee Lee Y, Lev A, AbuZaitun O, Rechavi E, Levy S, Simon AJ, Somech R
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0792
[summary] [PDF full-Text] [Supplemental Materials]

Efficacy of once-daily ophthalmic bilastine for the treatment of allergic conjunctivitis: a dose-finding study
Gomes PJ, Ciolino JB, Arranz P, Hernández G, Fernández N
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0800
[summary] [PDF full-Text]

Smell improvement by anti-IgE and anti-IL 5 biologics in patients with CRSwNP and severe asthma. A real life study
Barroso B, Valverde-Monge M, Alobid I, Olaguibel JM, Rial MJ, Quirce S, Arismendi E, Barranco P, Betancor D, Bobolea I, Cárdaba B, Cruz Carmona MJ, Curto E, Domínguez-Ortega J, González-Barcala FJ, Martínez-Rivera C, Mahíllo-Fernández I, Muñoz X, Picado C, Plaza V, Rodrigo Muñoz JM, Soto-Retes L, Valero A, del Pozo V, Mullol J, Sastre J
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0812
[summary] [PDF full-Text] [Supplemental Materials]

Exacerbations among patients with asthma are largely dependent on the presence of multimorbidity
Domínguez-Ortega J, Luna-Porta JA, Olaguibel JM, Barranco P, Arismendi E, Barroso B, Betancor D, Bobolea I, Caballero ML, Cárdaba B, Cruz MJ, Curto E, González-Barcala FJ, Losantos-García I, Martínez-Rivera C, Mendez-Brea P, Mullol J, Muñoz X, Picado C, Plaza V, del Pozo V, Rial MJ, Sastre J, Soto L, Valero A, Valverde-Monge M, Quirce S
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0816
[summary] [PDF full-Text] [Supplemental Materials]

A five-year open follow up of a randomized, double-blind placebo-controlled trial of intralymphatic immunotherapy for birch and grass reveals remaining beneficial effects
Hjalmarsson E, Hellkvist L, Karlsson A, Winquist O, Kumlien Georén S, Westin U, Olaf Cardell L
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0832
[summary] [PDF full-Text] [Supplemental Materials]

Understanding severe asthma through small and Big Data in Spanish hospitals - PAGE Study
Melero Moreno C, Almonacid Sánchez C, Bañas Conejero D, Quirce S, Álvarez Gutiérrez FJ, Cardona V, Sánchez-Herrero MG, Soriano JB, PAGE Study group
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0848
[summary] [PDF full-Text] [Supplemental Materials]

Sensitization to Vitis vinifera pollen in a wine production area. Identification of the allergens involved
González Mahave I, Lobera T, López-Matas MªA, Blasco A, Vidal I, Álvarez F, Carnes J
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0849
[summary] [PDF full-Text] [Supplemental Materials]

Bronchodilator reversibility in the GAN severe asthma cohort
Milger K, Skowasch D, Hamelmann E, Mümmler C, Idzko M, Gappa M, Jandl M, Körner-Rettberg C, Ehmann R, Schmidt O, Taube C, Holtdirk A, Timmermann H, Buhl R, Korn S
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0850
[summary] [PDF full-Text] [Supplemental Materials]

Very rapid improvement of extended nitric oxide parameters, associated with clinical and functional betterment, in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) treated with Dupilumab
Paoletti G, Casini M, Malvezzi L, Pirola F, Russo E, Nappi E, Quintina Muci G, Montagna C, Messina MR, Ferri S, Racca F, Lamacchia D, Cataldo G, Puggioni F, De Virgilio A, Ferreli F, Mercante G, Spriano G, Canonica GW, Heffler E
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0851
[summary] [PDF full-Text]

Weight loss and vitamin D improve hyporesponsiveness to corticosteroids in obese asthma
Bantulà M, Tubita V, Roca-Ferrer J, Mullol J, Valero A, Bobolea I, Pascal M, de Hollanda A, Vidal J, Picado C, Arismendi E
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0861
[summary] [PDF full-Text]

Characterization of relevant bovine dander allergen components
Airaksinen L, Suojalehto H, Lindström I, Sund J, Pallasaho P, Puustinen A
J Investig Allergol Clin Immunol 2024; Vol. 34(1)
doi: 10.18176/jiaci.0863
[summary] [PDF full-Text] [Supplemental Materials]

The influence of BMI in asthma. Which traits are due to obesity and which to asthma and obesity phenotype?
Esteban-Gorgojo I, Gorgojo MP, Sastre J, García-Río F, Quirce S
J Investig Allergol Clin Immunol 2024; Vol. 34(1)
doi: 10.18176/jiaci.0865
[summary] [PDF full-Text] [Supplemental Materials]

Co-sensitization to the three non-homologous major cashew allergens Ana o 1, Ana o 2 and Ana o 3 is caused by IgE cross-reactivity
Kabasser S, Radauer C, Eber E, Haber ME, Hieden K, Zieglmayer P, Kost LE, Sindher SB, Chinthrajah S, Geiselhart S, Hoffmann-Sommergruber K, Nadeau KC, Breiteneder H, Bublin M
J Investig Allergol Clin Immunol 2024; Vol. 34(1)
doi: 10.18176/jiaci.0867
[summary] [PDF full-Text] [Supplemental Materials]

Sputum Inflammatory Patterns are Associated with Distinct Clinical Characteristics in Subjects with Occupational Asthma Independently from the Causal Agent
Migueres N, Vandenplas O, Walusiak-Skorupa J, Wiszniewska M, Munoz X, Romero-Mesones C, Suojalehto H, Lindström I, van Kampen V, Merget R, Mason P, Maestrelli P, Sastre J, Quirce S, Rifflart C, Godet J, de Blay F
J Investig Allergol Clin Immunol 2024; Vol. 34(2)
doi: 10.18176/jiaci.0868
[summary] [PDF full-Text] [Supplemental Materials]

Prevalence, T2-biomarkers and cost of severe asthma in the era of biologics: The BRAVO-1 study
Domingo C, Sicras-Mainar A, Sicras-Navarro A, Sogo A, Mirapeix RM, Engroba C
J Investig Allergol Clin Immunol 2024; Vol. 34(2)
doi: 10.18176/jiaci.0871
[summary] [PDF full-Text]

Airway reactance predicts static lung hyperinflation in severe asthma
Yen-Jung L, Hsin-Kuo K, Sheng-Wei P, Jia-Yih F, Kang-Cheng S, Yang L, Sheau-Ning Y, Yi-Han H, Diahn-Warng P
J Investig Allergol Clin Immunol 2024; Vol. 34(2)
doi: 10.18176/jiaci.0888
[summary] [PDF full-Text] [Supplemental Materials]

IgE sensitization to Blo t 21 and Blo t 5 is associated with asthma in the tropics: a case-control study
Zakzuk J, Donado K, Mondol E, Marrugo V, Regino R, López JF, Hernández K, Mercado D, Dennis R, Puerta L, Caraballo L
J Investig Allergol Clin Immunol 2024; Vol. 34(3)
doi: 10.18176/jiaci.0892
[summary] [PDF full-Text] [Supplemental Materials]

Bilastine 0.6% preservative-free eye drops, a once-daily treatment for allergic conjunctivitis
Gomes PJ, Ciolino JB, Arranz P, Hernández G, Fernández N
J Investig Allergol Clin Immunol 2024; Vol. 34(3)
doi: 10.18176/jiaci.0894
[summary] [PDF full-Text] [Supplemental Materials]

Deconstructing adverse reactions to Amoxicillin-Clavulanic Acid: the importance of time of onset
Freundt-Serpa NP, Salas-Cassinello M, Gonzalo-Fernández A, Marchán-Pinedo N, Doña I, Serrano-García I, Humanes-Navarro AM, Bogas G, Labella M, Sánchez-Morillas L, Torres MJ, Fernández-Rivas M
J Investig Allergol Clin Immunol 2023; Vol. 34(3)
doi: 10.18176/jiaci.0896
[summary] [PDF full-Text]

Prevalence of Atopic Dermatitis in the adult population of Catalonia (Spain): a retrospective, large-scale population-based study
Mora T, Sánchez-Collado I, Mullol J, Muñoz-Cano R, Ribó P, Valero A
J Investig Allergol Clin Immunol 2024; Vol. 34(4)
doi: 10.18176/jiaci.0899
[summary] [PDF full-Text] [Supplemental Materials]

Prevalence of asthma in Catalonia (Spain): a retrospective, large-scale population-based study
Mora T, Sánchez-Collado I, Mullol J, Ribó P, Muñoz-Cano R, Valero A
J Investig Allergol Clin Immunol 2024; Vol. 34(4)
doi: 10.18176/jiaci.0903
[summary] [PDF full-Text] [Supplemental Materials]

Practitioner's Corner

Short Communications

Efficacy of mepolizumab in patients with concomitant severe eosinophilic asthma and severe chronic urticaria: an example of personalized medicine?
Antonicelli L, Tontini C, Garritani MS, Piga MA, Bilò MB
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0770
[summary] [PDF full-Text]

Selective allergy to whiff (Lepidorhombus whiffiagonis): identification of enolase as a new major allergen
Haroun-Díaz E, Martín-Pedraza L, Betancor D, Somoza ML, Blanca-López N, Vázquez de la Torre M, Luna L, Bartolomé B, Pastor-Vargas C, Cuesta-Herranz J, Ruano FJ
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0802
[summary] [PDF full-Text] [Supplemental Materials]

Is hen’s egg allergy decreasing among Japanese children in nurseries?
Tanaka Y, Yamanaka A, Motoyama Y, Kusunoki T
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0805
[summary] [PDF full-Text]

Recurrent bronchospasm in children attended in the emergency room
Marques-Mejias MA, Tomás-Pérez M, Hernández-Martin I, Loli-Ausejo D, Quirce S
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0810
[summary] [PDF full-Text]

COVID-19 Publications in Allergy Journals, 2020-2021: A Bibliometric Analysis
D´Amelio CM, Gastaminza G, Aquerreta I, Cacho-Asenjo E, Martinez-Simon A, Núñez-Córdoba JM
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0821
[summary] [PDF full-Text] [Supplemental Materials]

Treatment of severe atopic dermatitis with upadacitinib in real clinical practice. Short-term efficacy and safety results
Pereyra-Rodriguez JJ, Herranz P, Figueras-Nart I, Perez B, Elosua M, Munera-Campos M, Melgosa-Ramos J, Zaragoza V, Silvestre JF, Campos-Domínguez M, Guilabert A, Miquel J, Alcantara-Luna S, de la Cueva P, Serra-Baldrich E, Armario-Hita JC
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0831
[summary] [PDF full-Text]

Role of the different healthcare professionals in the management of asthma patients. The GEMA-FORUM IV task force
Quirce S, Trigueros JA, Ausín P, Muñoz Cano R, Ramírez Hernández M, González-Barcala FJ, Gregorio Soto J, Padilla Galo A, Cisneros Serrano C, Pueyo Bastida A, Pascual Erquicia S, Dávila I, Martínez Moragón E, Plaza Zamora FJ, Sánchez Barbero F, Plaza V, Domínguez-Ortega J, GEMAFORUM task force
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0833
[summary] [PDF full-Text] [Supplemental Materials]

Food protein-induced enterocolitis syndrome in an adult population from Spain
García Paz V, Carballeira Anca I, Romero Sánchez L, Otero Alonso A, González Torres L, Vila Sexto L
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0835
[summary] [PDF full-Text]

Spanish Survey of Food Protein-Induced Enterocolitis Syndrome
Infante S, Argiz L, Cabrera-Freitag P, Fernández-de-Alba I, Moya B, Escudero C, Pediatric Allergy Committee, Spanish Society of Allergy and Clinical Immunology (SEIAC).
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0828
[summary] [PDF full-Text] [Supplemental Materials]

Concomitant Efficacy of Dupilumab for severe atopic dermatitis and comorbid asthma in real-life conditions
Pose K, Laorden D, Hernández N, Villamañán E, Quirce S, Domínguez-Ortega J
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0837
[summary] [PDF full-Text]

First line versus second line use of reslizumab in severe uncontrolled asthma
Pérez de Llano LA, Cosío BG, Lobato Astiárraga I, Soto Campos G, Tejedor Alonso MA, Malanda NM, Padilla Galo A, Urrutia Landa I, Michel de la Rosa FJ, García-Moguel I, Reslizumab real-life Spanish group
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0839
[summary] [PDF full-Text] [Supplemental Materials]

Validation of the algorithm for the monitoring and control of asthma through telemedicine. The Consensus COMETA Project.
Almonacid Sánchez c, Blanco-Aparicio M, Domínguez-Ortega J, Giner Donaire J, Molina Paris J, Sánchez Marcos N, Plaza V
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0841
[summary] [PDF full-Text] [Supplemental Materials]

SARS-CoV-2 Infection among Patients with Mastocytosis: An EPICOVIDEHA Report
Criscuolo M, Salmanton-García J, Fracchiolla N, Dragonetti G, Khanna N, Weinbergerová B, Schönlein M, Machado M, Labrador J, Kolditz M, Itri F, Gomes da Silva M, Bonuomo V, Sciumè M, Nunes Rodrigues R, Gräfe S, Marchesi F, Cornely OA, Pagano L
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0845
[summary] [PDF full-Text] [Supplemental Materials]

A pilot experience using a one-bag intravenous rapid desensitization protocol for chemotherapeutics and biologics in a cohort of patients with access to a delabeling pathway
Vázquez-Revuelta P, Lleonart-Bellfill R, Molina-Mata K, Muñoz-Sánchez Pharm C, Rey-Salido Pharm M, Madrigal-Burgaleta R
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0860
[summary] [PDF full-Text] [Supplemental Materials]

Stability over time of in-hospital compounded amoxicillin capsules and ceftriaxone patch tests for drug allergy testing
Gondé H, Belaid I, Lamoureux F, Martinet J, Varin R, Tétart F, Hervouët C
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0864
[summary] [PDF full-Text] [Supplemental Materials]

Lung function abnormalities and their correlation with clinical characteristics and inflammatory markers in adult asthma
Betancor D, Olaguibel JM, Rodrigo-Muñoz JM, Alvarez Puebla MJ, Arismendi E, Barranco P, Barroso B, Cárdaba B, Cruz MJ, Curto E, Del Pozo V, Domínguez-Ortega J, González-Barcala FJ, Luna-Port JA, Martínez-Rivera C, Mullol J, Muñoz X, Picado C, Plaza V, Quirce S, Rial MJ, Soto-Retes L, Valero A, Valverde-Monge M, Sastre J
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0866
[summary] [PDF full-Text] [Supplemental Materials]

Relationship between immunoglobulin-E deficiency and autoimmune disease: the paradigm of primary biliary cholangitis
Porto-Soto A, Sopeña B, Freire M, Mosquera M, Alonso-Sampedro M, Gude F, Vidal C, González-Quintela A
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0869
[summary] [PDF full-Text] [Supplemental Materials]

Early effectivity of dupilumab in patients with t2 severe asthma: a prospective real-life study
Castilla-Martínez M, Andújar-Espinosa R, Flores-Martín I, Reyes Cotes MH, Cabrejos-Perotti S, Miralles-López JC, Carbonell-Martínez A, Bravo-Gutiérrez FJ, Valverde-Molina J, Pérez-Fernández V, RE-ASGRAMUR GROUP
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0872
[summary] [PDF full-Text] [Supplemental Materials]

Validation of the Asthma Impairment and Risk Questionnaire (AIRQ) in Spain: a useful tool to assess asthma control in adolescent and adult patients
Pérez de Llano L, Martínez Moragón E, Entrenas LM, Martínez Rivera C, Cisneros C, Blanco-Aparicio M, Trisán A, Plaza V, Ramos J, Funenga Fitas E, Sanchez-Covisa J, Dominguez-Ortega J
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0881
[summary] [PDF full-Text] [Supplemental Materials]

A Prospective Validation of a Diagnostic Algorithm for Hypersensitivity Reactions to COVID-19 Vaccines
Rodríguez-Otero N, Granados-Alarcón E, Antolín-Amérigo D, Solórzano-Zepeda C, Blázquez-Fernández M, Grandal-Platero M, De la Hoz-Caballer B
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0877
[summary] [PDF full-Text] [Supplemental Materials]

A clustered schedule for venom immunotherapy with a depot extract: reaching the target in 7 days
Cadavid-Moreno S, González-Fernández T, Méndez-Brea P, Armisén M, Vidal C
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0879
[summary] [PDF full-Text] [Supplemental Materials]

COVID-19 as a turning point in the need for specialized units for the sense of smell
Izquierdo-Domínguez A, Calvo-Henríquez C, Ceballos JC, Rodriguez-Iglesias M, Mullol J, Alobid I
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0891
[summary] [PDF full-Text] [Supplemental Materials]

Mepolizumab treatment for severe eosinophilic asthma: a 5-years real-life experience
Loli-Ausejo D, Perdomo G, Mascaró B, Martínez-Olondris P, Sánchez-Fernández MC, Mullol J, Valero A, Arismendi E, Bobolea I
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0898
[summary] [PDF full-Text] [Supplemental Materials]

Analysis of Lymphocyte and Clinical Profile among Non-monogenic Common Variable Immunodeficiency Patients with and without Class Switch Recombination Defect
Zavareh FT, Mirshafiey A, Yazdani R, Keshtkar AA, Abolhassani H, Kiaee F, Parvaneh N, Shariat M, Rezaei N, Aghamohammadi A
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0900
[summary] [PDF full-Text] [Supplemental Materials]

Case Reports

Dupilumab remarkably improved eustachian tube obstruction: a case of mepolizumab-resistant eosinophilic otitis media
Takeshita Y, Tada Y, Okano M, To M, To Y
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0803
[summary] [PDF full-Text] [Supplemental Materials]

Two new allergens in a watermelon (Citrullus lanatus) allergy episode
Carpio-Escalona LV, Fernández-Lozano C, Peracho L, Martínez-Alonso E, Rita CG, Martínez-Botas J, Alcázar A, de la Hoz Caballer B
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0804
[summary] [PDF full-Text] [Supplemental Materials]

Pistachio allergens: the long journey between mother and daughter
Villalobos V, Betancor D, Pastor-Vargas C, Martin L, Cuesta J, Rodríguez del Río P, Escudero C
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0806
[summary] [PDF full-Text]

Myosin heavy chain, an allergen involved in anaphylaxis to shrimp head
Saenz de San Pedro B, López Guerrero A, Navarrete del Pino MA, Alcántara Villar M, Álvarez F, López-Matas MA, Carnés J
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0807
[summary] [PDF full-Text]

Selective allergy to wedge sole fish (Dicologlossa cuneata) due to Beta Parvalbumin
Bartha I, Ramos T, Pineda F, Vega F, Belver MT, Blanco C
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0809
[summary] [PDF full-Text] [Supplemental Materials]

Acute sialadenitis to a gadolinium contrast media
Beriziky P, Bara C, Lemeunier V, Mear A, Maillard H
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0811
[summary] [PDF full-Text] [Supplemental Materials]

Polyethylene glycol allergy: risks of skin testing and complement mediated anaphylaxis
Chiang V, Kan AKC, Yeung HHY, Au EYL, Sing Lau CH, Li PH
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0813
[summary] [PDF full-Text]

The Lymphocyte Transformation Test in delayed hypersensitivity reactions induced by ibuprofen and/or metamizole
Nin-Valencia A, Domínguez-Ortega J, Cabañas R, Sánchez H, Fiandor A, Lluch M, Ramirez E, Gómez-Traseira C, Rodríguez A, González-Muñoz M
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0814
[summary] [PDF full-Text] [Supplemental Materials]

IL-9R loss in innate lymphoid cell type 2 (ILC2) reflects Treg impairment in mastocytosis patients
Ercolano G, Trabanelli S, Jandus C, Jandus P
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0815
[summary] [PDF full-Text] [Supplemental Materials]

Eosinophilic sialodochitis: a rare comorbidity of severe asthma
González O, Picado C, Alobid I, Ramirez J, Arismendi E, Valero A, Bobolea I
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0817
[summary] [PDF full-Text]

Allergy to white kidney beans with cross-reactivity to red kidney beans. Report of two cases in children
Laiseca García J, Díaz de Durana A, Gónzalez Bravo L, Pineda De la Losa F, Macías Iglesias J, Rosado A
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0818
[summary] [PDF full-Text] [Supplemental Materials]

Occupational rhinitis due to coati allergy and cross-reactivity with dog serum albumin
Haroun Díaz E, Vázquez de la Torre M, Somoza ML, Blanca-López N, Martín-Pedraza L, Prieto-Moreno A, Bartolomé B, Cuesta-Herrnaz J, Ruano FJ
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0827
[summary] [PDF full-Text]

Millet: A Gluten-free and healthy cereal with the potential to induce anaphylaxis
Baptista Serna L, Sastre B, Rodrigo-Muñoz JM, Valverde-Monge M, Sastre J, del Pozo V
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0826
[summary] [PDF full-Text] [Supplemental Materials]

Tolerance to SARS-CoV-2 mRNA vaccination in a patient with challenge-confirmed PEG 2000 allergy
Faihs V, Bent R, Darsow U, Biedermann T, Brockow K
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0829
[summary] [PDF full-Text]

Safe administration of SARS-CoV-2 vaccine after desensitization to a biologic containing polysorbate 80 in a patient with polyethylene glycol-induced severe anaphylaxis and sensitization to polysorbate 80
Nin-Valencia A, Fiandor A, Lluch M, Quirce S, Caballero T, Heredia Revuelto R, González-Muñoz M, Caballero ML, Cabañas R
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0830
[summary] [PDF full-Text] [Supplemental Materials]

What is the limit? Anaphylaxis after whey sport supplement shake intake in a cow’s milk tolerant patient
Villalobos-Vilda C, Lendínez MA, Lorente-Sorolla C, Rodrigo-Muñoz JM, Del Pozo V
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0836
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis to European perch (Perca fluviatilis) due to alpha-actin protein
González-Bravo L, Alonso-Díaz-de-Durana MD, Pastor-Vargas C, Bartolomé-Zavala B
J Investig Allergol Clin Immunol 2023; Vol. 33(2)
doi: 10.18176/jiaci.0825
[summary] [PDF full-Text] [Supplemental Materials]

Effect of dupilumab in a patient with severe asthma complicated with recurrent anaphylaxis: a case report
Otani T, Iwamoto H, Horimasu Y, Yamaguchi K, Sakamoto S, Masuda T, Miyamoto S, Nakashima T, Fujitaka K, Hamada H, Hattori N
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0840
[summary] [PDF full-Text]

Covid-19 vaccine tolerabilty in a patient with a delayed allergic reaction to polyethylene glycol: a case report
Loli-Ausejo D, Gómez-Armayones S, Sáez-Peñataro J, González-Matamala MF, Mascaró B, Muñoz-Cano R, Bartra J
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0843
[summary] [PDF full-Text] [Supplemental Materials]

Remdesivir-induced non-immediate cutaneous hypersensitivity reaction
Galleani C, Bautista-Villanueva S, Piorno I, Moya B, Mielgo R, Gil M, Crespo JF
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0844
[summary] [PDF full-Text]

Avocado allergy. Identification of a new allergen
Privitera-Torres M, González- Moreno A, Pérez-Codesido S, del Pozo Abejón V, Rodrigo Muñoz JM, Cañas Mañas JA, Alonso- Díaz- de Durana MD
J Investig Allergol Clin Immunol 2023; Vol. 33(3)
doi: 10.18176/jiaci.0846
[summary] [PDF full-Text]

Different tolerance of food protein-induced enterocolitis syndrome in fishes of the same family: A pediatric case report
Tsukahara A, Fujita M, Okamoto Y, Tsumagari S, Takamasu T, Inuo C
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0847
[summary] [PDF full-Text]

Use of concentrated plasma-derived subcutaneous C1 inhibitor as long-term prophylaxis in an 8-year-old child with hereditary angioedema
Lasa EM, Herrero L, Martínez S, Arruti N, Oliver P, Joral A
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0855
[summary] [PDF full-Text] [Supplemental Materials]

Allergy IgE-mediated to Pembrolizumab and Successful Desensitization
Torrado I, Peña MªI, Tsopana A, Mendoza I, Beitia JM, Mateo B, Chara LE, Vega A
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0858
[summary] [PDF full-Text]

Severe anaphylactic reaction to ferric carboxymaltose with positive skin and basophil activation tests
Moreaux S, Hammoud R, Beauvillain C, Babin M, Husser Vidal S, Nicolie B, Morisset M
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0870
[summary] [PDF full-Text] [Supplemental Materials]

Kounis syndrome after lidocaine use
Garcia-Nunez I, Algaba-Marmol MA, Ignacio-Garcia JM
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0876
[summary] [PDF full-Text]

11S globulin identified as a new bean allergen
Gómez-López A, Fernández-Bravo S, Nuñez-Borque E, Betancor Pérez D, Bernaola Abraira M, Esteban Vázquez V, Pastor-Vargas C, Cuesta-Herranz J, Ibáñez Sandín MD, Escudero Díez C
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0873
[summary] [PDF full-Text]

Allergens responsible of Olive fruit ingestion anaphylaxis
Prados-Castaño M, Reguero-Capilla M, Bartolomé B, Ochando Díez-Canseco M, Quiralte J
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0880
[summary] [PDF full-Text]

Allergy to Rivaroxaban Cross-Reactivity with other Direct Anticoagulants and the Role of the Basophil Activations Test: A Case Report
Tomás-Pérez M, De las Vecillas L
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0883
[summary] [PDF full-Text] [Supplemental Materials]

Kale allergy, a new member in LTP syndrome
Rodríguez-Otero N, Fernández-Lozano C, Elías-Sáenz I, Bernal-Rubio L, Vaquero-Rey A, Martínez-Botas J, de la Hoz-Caballer B
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0885
[summary] [PDF full-Text]

Allergy to persimmon (Diospyros kaki): A Chitinase and Thaumatin like protein, two new identified allergens
Betancor D, Gomez-Lopez A, Nuñez-Borque E, Fernandez-Bravo S, Barroso B, Esteban V, Pastor-Vargas C, Cuesta-Herranz J
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0886
[summary] [PDF full-Text] [Supplemental Materials]

Hennekam syndrome due to a novel homozygous CCBE1 mutation presenting as pediatric-onset CVID
Tessarin G, Baronio M, Gazzurelli L, Rossi S, Chiarini M, Moratto D, Badolato R, Lougaris V
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0895
[summary] [PDF full-Text] [Supplemental Materials]

Application of different in vitro tests for the precise diagnosis of double sensitization to Vespula-Polistes
Giraldo-Tugores M, Vaquero-Rey A, Santacruz-Santos M, Rodríguez-Martín E, De Andrés A, Ballester-González R, Barra-Castro A, Fernández-Lozano C, Martínez-Botas J, Antolín-Amérigo D
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0890
[summary] [PDF full-Text] [Supplemental Materials]

Sheep cheese allergy in Alpha-gal Syndrome
German-Sanchez A, Alonso-Llamazares A, Latorre-Ibañez MD, Bartolome-Zavala B, Antepara-Ercoreca I
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0897
[summary] [PDF full-Text]

Kounis Syndrome and Vanadium allergy: heed your hunch
Giraldo-Tugores M, Sanmartín-Fernández M, Fernández-Lozano C, Martínez-Botas J, De-la-Hoz-Caballer B, González-de-Olano D
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0884
[summary] [PDF full-Text] [Supplemental Materials]

Letters to the Editor

Exhaled breath temperature is not helpful to identify cellular bronchitis in severe asthma
Moya B, Huang C, Kjarsgaard M, Martín-Arriscado C, Nair P
J Investig Allergol Clin Immunol 2023; Vol. 33(4)
doi: 10.18176/jiaci.0862
[summary] [PDF full-Text] [Supplemental Materials]

Changes of Thymus and Activation-Regulated Chemokine in Type 2 Inflammatory Disease Patients with Dupilumab Treatment
Zhou B, Liang S, Shang S, Xiang L, Li L
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0874
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis in a Central University Hospital - A two decade comparison study
Miranda J, Caires A, Botelho C, Rodrigues Cernadas J
J Investig Allergol Clin Immunol 2023; Vol. 33(5)
doi: 10.18176/jiaci.0889
[summary] [PDF full-Text]

Reply to ´Management of Patients with Suspected or Confirmed Antibiotic Allergy´
Barroso B, Gómez-López A, Valverde-Monge M
J Investig Allergol Clin Immunol 2023; Vol. 33(6)
doi: 10.18176/jiaci.0901
[summary] [PDF full-Text]