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Anaphylaxis to Tranexamic Acid: 2 Cases Confirmed by Drug Provocation Test, What about Skin Tests?

El Hanache H1, Verdaguer M2, Collin L1, Babin M3, Favrelière S4, Vidal Husser S5, Maissiat MH6, Hoppe A1, Morisset M1

1Allergy unit, Angers University Hospital, Angers, France
2RegionalAllergology Center, Poitiers University Hospital, Poitiers, France
3Department of Pharmacology toxicology and Pharmacovigilance unit, Angers University Hospital, Angers, France
4Department of Pharmacology and Pharmacovigilance unit, Poitiers University Hospital, Poitiers, France
5Department of Anaesthesia and Reanimation, Angers University Hospital Angers, France
6Department of Anaesthesia and Reanimation, Saint Léonard Clinic, Trélazé, France

J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0651

Key words: Tranexamic acid, Anaphylaxis, Anaesthesia, Skin testing, Drug provocation test