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The Spanish multidisciplinary research network for allergic diseases

MJ Torres1-4, Agundez J5, Barber D6, Bartra J7,8, Davila I9, Escribese MM10, Fernandez-Rivas M11, Ferrer M12, Perez-Inestrosa E3,13, Villalba M14, Mayorga C1-3

1Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga
2Allergy Clinical Unit, Hospital Regional Universitario de Málaga, Málaga
3Centro Andaluz de Nanomedicina y Biotecnología-BIONAND, Málaga
4Medicine Department, Universidad de Málaga-UMA, Málaga
5University Institute of Molecular Pathology Biomarkers, UEx, Cáceres; ARADyAL Instituto de Salud Carlos III, Spain
6School of Medicine, Institute for Applied Molecular Medicine, Universidad CEU San Pablo, Madrid
7Allergy Section, Pneumology Department, Institut Clínic Respiratori (ICR), Hospital Clínic de Barcelona, Barcelona
8Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona
9Allergy Service, University Hospital of Salamanca, Salamanca, Spain. Department of Biomedical and Diagnostics Sciences, Faculty of Medicine, University of Salamanca, Salamanca, Spain. Institute for Biomedical Research of Salamanca (IBSAL), Salamanca
10School of Medicine, Department of Basic Medical Sciences, Universidad CEU San Pablo, Madrid
11Allergy Dept. Hospital Clínico San Carlos, Universidad Complutense, IdISSC, ARADyAL, Madrid
12Department of Allergy and Clinical Immunology, Clínica Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona
13Departamento de Química Orgánica, Universidad de Málaga-IBIMA, Málaga
14Biochemistry and Molecular Biology Department, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid

J Investig Allergol Clin Immunol 2021; Vol. 31(2)
doi: 10.18176/jiaci.0629

Thematic networks of cooperative health research (RETICS) are organisational structures promoted by the Instituto de Salud Carlos III of the Spanish Ministry of Science with the objective of carrying out cooperative research projects addressing challenges of general interest for the society in the health field. The RETICS of Asthma, Adverse Drug Reactions and Allergy (ARADyAL) was funded in 2016 for a 5 years programme (2017-2021). ARADyAL integrates basic and clinical research in the areas of allergy, immunology, genetics, nanomedicine, pharmacology, and chemistry, with special interest in the research of new biomarkers, and the design and evaluation of new intervention strategies for allergic patients with severe phenotypes.
The consortium is composed by 28 groups across Spain, which includes 171 clinical and basic researchers: 17 clinical groups that cover more than 10.000.000 patients of all ages and from urban and rural areas; and 11 basic groups that develop their activities mostly at university and research institutes. ARADyAL has proposed a research program organised in three different areas focused on Precision Medicine: Program 1. Mechanisms and prediction of adverse drug reactions and allergic diseases; Program 2. Towards a precise diagnosis of allergic diseases; and Program 3. Predicting interventions in allergic diseases. There is also one transversal program dedicated to training. The network has a Direction Committee and an External Advisory Scientific Committee, which advise the global network coordinator who has recognised expertise in the field. ARADyAL is a unique meeting-point for clinicians and basic scientists that are already working on allergy.

Key words: Allergy. Research. Networks. Biomarkers. Mechanism. Diagnosis. Treatment