The Journal of Investigational Allergology and Clinical Immunology (J Investig Allergol Clin Immunol) provides an attractive and very active forum for basic and clinical research in allergology and clinical immunology. The journal publishes original works, reviews, short communications and opinions. It is the Official Journal ofthe Spanish Society of Allergology and Clinical Immunology (SEAIC). The journal will appear bimonthly (6 issues each year). The peer-review system, based on a team of internationally renowned and committed editors, guarantees the scientific quality of the papers.

Current ISSUE


2025; volume 35, Issue 3
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Review

Prostaglandin E2: A Potential Link Between NSAIDs and the Menstrual Cycle, Cofactors of Food-Dependent Anaphylaxis
Tubita V, Mir Ihara P, González-Matamala MF, Picado C, Muñoz Cano RM
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Position Paper on the Treatment of Eosinophilic Esophagitis With Dupilumab
Tomás-Pérez M, Domenech-Witek J, Ávila-Castellano MR, Carballas-Vázquez C, Vásquez-Bautista AA, Jover-Cerdá V, González-Mendiola R
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Original Articles

A Deep Intronic Polymorphism at 9q21.11 Contributes to the Risk of Atopic Dermatitis Through Methylation-Regulated Expression of Tight Junction Protein 2
Lim YYE, Sio YY, Say YH, Reginald K, Chew FT
[summary] [PDF full-Text] [Supplemental Materials]

Investigating Sensitization to Novel Foods: A Real-Life Prevalence Study of IgE-Mediated Reactivity to Cricket, Locust, and Mealworm in Insect Food-Naïve Allergic Individuals
Scala E, Abeni D, Villella V, ViIlalta D, Cecchi L, Caprini E, Asero R
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Mast Cell Activation Profile and TFH13 Detection Discriminate Between Food Anaphylaxis and Sensitization
Ollé L, García-García L, Ruano-Zaragoza M, Bartra J, González-Navarro EA, Pérez M, Roca-Ferrer J, Pascal M, Martín M, Muñoz-Cano R
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Practitioner's Corner

Short Communications

Generalized Eczema as a Transient Paradoxical Adverse Effect of Dupilumab
Betancor D, Valverde-Monge M, Díaz-Recuero JL, Jo-Velasco ME, Del Pozo V, Sastre J
[summary] [PDF full-Text] [Supplemental Materials]

Predictive Factors and Optimization of Omalizumab in Chronic Spontaneous Urticaria: A Multicenter Study of 257 Patients
Ceravalls J, Giménez-Arnau AM, Expósito-Serrano V, Fernández Chico N, Lara Moya A, Bielsa I, Ribó P, Mascaró-Hereza B, Bonfill-Ortí M, Spertino J, Serra E, Baliu-Piqué C, Melé-Ninot G
[summary] [PDF full-Text] [Supplemental Materials]

Bioinformatics-Based Prediction of B- and T-Cell Epitopes in R-Mandelonitrile Lyase, a Recently Described Peach Allergen
López-Matas MÁ, Martín-López L, Vílchez-Sánchez F, Pedrosa M, Rodríguez-Pérez R, Domínguez-Ortega J, Carnés J
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Revisiting the Impact of Misdiagnosed Drug Hypersensitivity in Hospitalized Patients: A 10-Year Perspective
Bernaola J, Otal-Buesa M, Barroso B, Valverde-Monge M, Sastre J
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Safety and Efficacy of the First Venom Immunotherapy for Allergy to Vespa velutina nigrithorax: Interim Analysis of the W-STING Study
Carballada F, Parra A, Liñares T, Giangrande N, Varela S, Meijide Á, Castro M, Tabar AI
[summary] [PDF full-Text] [Supplemental Materials]

Use of a 24-Hour Hotline vs Voicemail for Off-Hour Support During Oral Immunotherapy for Food Allergy
Paradis V, Des Roches A, Elbany C, Braun C, Graham FJ, Samaan K, Labrosse R, Paradis L, Bégin P
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Case Reports

Measurement of Fecal Calprotectin and Zonulin as Biomarkers in Adults With Fish-Induced Food Protein-Induced Enterocolitis Syndrome
Entrala A, Lluch-Bernal MM, Domínguez-Ortega J, Molero-Luis M, Crespo Sánchez G, Quirce S, Rodríguez-Perez R
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Hidden Dangers of Oral Contrast Media: Delayed Hypersensitivity to Sodium Amidotrizoate and Meglumine Amidotrizoate (Gastrografin)
Pardo-Manrique V, Amat-Samaranch V, Pascal M, Loli-Ausejo D, Sánchez-Fernández MC, Ruano-Zaragoza M
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis Induced by Milk Thistle (Silybum marianum) Seed Ingestion: A Case Report
Planas-Vinos M, Sala-Cunill A, Luengo O, Castillo Fernandez M, Galvan-Blasco P, Cardona V, Guilarte M, Labrador-Horrillo M, Gil-Serrano J
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Letters to the Editor

Component-Based Assessment of the Main Allergens in Honeybee Venom in a Spanish Allergic Population
Carballada González F, Abel-Fernández E, González Guzmán LA, Pineda de la Losa F
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Ongoing Concerns With Honeybee Venom Immunotherapy
Khan S
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