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Case Report |
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Allergic eosinophilic gastroenteritis in a child with
Crohn’s disease |
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R. Tella1,
P. Gaig1,
M. Lombardero2,
P. García-Ortega1,
J. Bartra1,
M. Papo3,
X. Batlle4 |
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1 Allergy Unit, 3 Gastroenterology
Unit and 4 Pediatric Unit, Hospital Universitari Joan
XXIII, Institut d’Estudis Avançats, Universitat Rovira i
Virgili, Tarragona. 2 ALK-Abelló, Madrid, Spain |
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J Invest Allergol Clin Immunol
2004; Vol. 14(2): 159-161 |
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Abstract |
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A case of a child
with Crohn’s disease
who developed an
eosinophilic
gastroenteritis is
reported.
Although symptoms of
eosinophilic
gastroenteritis at
age 8 could mimic
those of Crohn’s
disease, laboratory,
radiographic and
histologically
studies are clearly
different.
Peripheral blood
eosinophilia (7,476
cells per mm3), high
serum IgE level
(1,050 kU/l) and
normal C-reactive
protein and
erythrocyte
sedimentation rate
are common in
eosinophilic
gastroenteritis and
uncommon in Crohn's
disease.
Eosinophilic
gastroenteritis was
due to bovine serum
albumin (BSA)
hypersensitivity,
confirmed with skin
tests, serum levels
to specific IgE and
a SDS-PAGE
IgE-immunoblotting.
A strict meat-free
diet was started,
with progressive
relief of symptoms
and decrease of
eosinophil count
twelve months later;
the patient became
fully symptom-free
and eosinophil count
was normal.
Key words:
Bovine seroalbumin,
Crohn’s disease,
eosinophilic
gastroenteritis,
food allergy |
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