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Original Article |
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Paradoxical coexistence of atopic
asthma and Human T-Lymphotropic Virus Type I (HTLV-I)
infection: a case report |
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A. Souza-Machado1, Á.
A. Cruz1, T. Sena Galvão1, André
Muniz2, A. Porto2, S. Braga (Pharm),
E. Marcelino Carvalho2 |
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Center for Respiratory Diseases (CER)1
and Immunology Department2 of Professor
Edgard Santos University Hospital, Faculty of Medicine,
Federal University of Bahia, Salvador, Bahia, Brazil. |
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J Invest Allergol Clin Immunol
2004; Vol. 14(4): 348-351 |
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Abstract |
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In this case report,
the authors report
the presence of two
supposedly antagonic
immune diseases in
thesame patient. The
patient is a 45-year-old
white woman with a
history of asthma
and allergic
rhinitis for the
last 10 years.
Asthmatic symptoms
were present and
were triggered after
exposure to dust and
mold. Her Human
TLymphotropic Virus
Type I (HTLV-I)
seropositive status
was detected by
chance five years
ago during a routine
screening for blood
donation. Skin prick
tests were positive
for Dermatophagoides
pteronyssinus,
Dermatophagoides
farinae and Blomia
tropicalis. Cytokine
levels in
unstimulated
cultures were: IFNγ
= 1195 pg/ ml, TNF∝
= 460 pg/ml, IL5 =
41 pg/ml and IL10 =
265 pg/ml.
Key words:
asthma, interferon,
allergy and
retrovirus. |
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