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Background:
Ipe is a resistant
hardwood that
contains
naphtoquinones. It
is easily found and
frequently used in
South and Central
America.
Naphtoquinones are
skin sensitizers.
Objective: To
describe a case of
occupational asthma
related to Ipe wood
dust.
Methods: The
patient was
submitted to a
clinical evaluation
consisting of a
respiratory symptom
questionnaire,
occupational history,
serial measurements
of lung function by
spirometry, skin
prick tests, patch
tests, specific IgE
and specific
bronchial
provocation tests to
Ipe dust.
Results: Serial
lung function
measurements showed
sustained regression
of obstruction
following removal
from exposure. Skin
prick tests, but not
patch tests, were
positive to Ipe, and
a specific bronchial
challenge showed a
late asthmatic
reaction. Specific
IgE search was
negative.
Conclusions:
Exposure to Ipe wood
dust can lead to
occupational asthma.
The underlying
mechanism should be
investigated.
Key words:
occupational asthma,
wood dusts, Ipe wood,
Tabebuia spp,
specific bronchial
provocation tests |