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We performed a
prospective
observational study
to establish a
relationship between
pollen counts of
Chenopodiacea/Amaranthacea
and clinical
symptoms of
rhinoconjunctivitis
and asthma in a
group of
monosensitised
patients.
Material and Methods.
A total of 60
patients (19 with
asthma) were
included in the
study. All patients
collected daily
symptom scores
during the summer
months of 1999, 2000
and 2001. The
questionnaire
included ocular,
nasal and pulmonary
symptoms. Pollen
counts were
expressed as pollen
grains/m3. Symptom
scores and pollen
counts were
correlated using
correlation
coefficients and Log
transformed
variables.
Results: In the
3 seasons studied we
identified a peak of
pollen and clinical
symptoms in the
second half of
August and first
half of September .
In 1999, there was a
significant positive
correlation between
total symptoms and
daily pollen grains/m3
(p<0.005, r =
0.347). This
correlation was not
significant for the
summers of 2000 and
2001.
After further
analysis, and by
displacing one of
both variables
between 11 to 17
days, the
correlation
coefficients for
total symptoms,
improved for 1999 (r
= 0. 744; p <
0.0001) and became
significant for 2000
(r = 0. 521; p <
0.0001) and 2001 (r
= 0.635; p <
0.0001).
Conclusion: We
identified a
significant time lag
between pollen
counts and symptom
scores in S. kali
monosensitized
patients. |