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M Morales Suárez-Varela,1,2,3
L García-Marcos Álvarez,4 MD Kogan,5
J Costa Ferreira,6 A Martínez Gimeno,7
I Aguinaga Ontoso,8 C González Díaz,9
A Arnedo Pena,10 B Domínguez Aurrecoechea,11
R María Busquets Monge,12 A Blanco Quiros,13
J Batlles Garrido,14 N García de Andoain,15
Á López-Silvarrey Varela,16 A García Merino,17
N Gimeno Clemente,1,2 A Llopis González1,2 |
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1Unit of Public Health, Hygiene, and
Environmental Care, Department of Preventive Medicine,
University of Valencia, Valencia, Spain
2CIBER Epidemiology and Public Health (CIBERESP), Spain
3Research Foundation, Hospital Universitario Dr. Peset,
Valencia, Spain
4Unit of Clinical Research (Cartagena) and Department of
Pediatrics, University of Murcia, Murcia, Spain
5HRSA, Maternal and Child Health Bureau, Rockville, USA
6 School of Public Health, University of Sao Paulo, Sao
Paulo, Brazil
7Section of Pediatric Pneumo-Allergy, Hospital Infantil
12 de Octubre, Madrid, Spain
8Department of Health Sciences. Public University of
Navarre, Navarre, Spain
9Department of Pediatrics, Hospital of Basurto, Bilbao,
Spain
10Section of Epidemiology. Centre of Public Health.
Regional Ministry of Health, Castellón, Castellón, Spain
11Health Centre of Otero, Oviedo, Oviedo, Spain
12Department of Pediatrics, Hospital del Mar, Barcelona,
Spain
13Department of Pediatrics, University of Valladolid,
Valladolid, Spain
14Department of Pediatrics, Hospital Torrecárdenas,
Almería, Spain
15Department of Pediatrics, Hospital de Donostia, San
Sebastián, Spain
16Foundation María José Jove, A Coruña, Spain
17Health Centre of Moreda, Health Service of Principado
de Asturias, Spain |
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Abstract |
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Background:
The prevalence of
atopic dermatitis
(AD), a chronic skin
disease, has
increased
substantially in
recent decades, and
different factors
have been implicated
in its etiology.
Although dietary
habits are being
investigated, few
conclusive findings
have been reported.
Nevertheless,
increased
consumption of
polyunsaturated
fatty acids (PUFA)
and a diet poor in
antioxidants have
been related to AD.
Objectives:
The objectives of
this study were to
investigate the
association between
AD, the intake of
different foods, and
the effect of a
Mediterranean diet
among Spanish
schoolchildren aged
6 to 7.
Methods: We
performed a
cross-sectional
study with 20 106
schoolchildren aged
6-7 years from 10
different areas of
Spain. The
participation rate
was 76.50%. The
prevalence of AD was
assessed using the
International Study
of Asthma and
Allergies in
Childhood
questionnaire and
the criteria of the
Spanish Academy of
Dermatology. To
calculate the
Mediterranean diet
score, we classified
food into 2 groups:
Mediterranean food,
including fruit,
seafood, vegetables,
pulses, cereals,
pasta, rice, and
potatoes; and
non-Mediterranean
food, including
meat, milk, and fast
food.
Results: Milk
was negatively
associated with AD.
Butter and nuts also
were negatively
associated, although
statistical
significance was
only reached when
these foods were
consumed 3 or more
times a week.
Conclusions:
We found no
association between
the Mediterranean
diet score and AD
and a positive
association between
AD and obesity.
Key words:
Atopic dermatitis.
Children. ISAAC
phase III.
Mediterranean diet.
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