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Rondón C1, Dávila I2,
Navarro Pulido AM3, Sánchez MC4,
Montoro J5, Matheu V6, Lluch-Bernal
M7, Fernández-Parra B8, Ibáñez MD9,
Dordal MT10, Colás C11, Antón E12,
Valero A13; Rhinoconjunctivitis Committee;
Spanish Society of Allergy and Clinical Immunology |
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1Allergy Unit, Regional
University Hospital of Malaga, IBIMA, UMA, Malaga, Spain
2Allergy Service, University Hospital of
Salamanca, Instituto de Investigaciones Biosanitarias de
Salamanca, IBSAL, Salamanca, Spain
3Allergy UGC-IC, Hospital El Tomillar, Dos
Hermanas, Sevilla, Spain
4Allergy Unit, CE Virgen de la Cinta,
Hospital Juan Ramón Jimenez, Huelva, Spain
5Allergy Unit, Hospital Universitario Arnau
de Vilanova, Facultad de Medicina, Universidad Católica
de Valencia San Vicente Mártir, Valencia, Spain
6Allergy Service, Hospital del Tórax (Ofra),
Complejo Hospitalario Universitario NSC and Unidad de
Investigación, Hospital Universitario NS Candelaria,
Tenerife, Spain
7Allergy Service, Hospital Virgen del Valle,
Toledo, Spain
8Allergy Service, Hospital El Bierzo,
Ponferrada, León, Spain
9Allergy Service, Hospital Infantil
Universitario Niño Jesús, Madrid, Spain
10Allergy Service, Hospital Municipal de
Badalona, Badalona, Spain and Allergy Service, Sant Pere
Claver Fundació Sanitària, Barcelona, Spain
11Allergy Service, Hospital Clínico-Instituto
de Investigación Sanitaria Aragón, Zaragoza, Spain
12Allergy Service, University Hospital
Marqués de Valdecilla, Santander, Spain
13Allergy Unit, Servei de Pneumologia i
Al·lèrgia Respiratòria, Hospital Clínic, Barcelona,
Spain and Institut dInvestigacions Biomèdiques August
Pi i Sunyer (IDIBAPS) Centro de Investigación Biomédica
en red en Enfermedades Respiratorias (CIBERES), Spain |
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Abstract |
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Background:
Nasal polyposis (NP)
is a chronic
inflammatory disease
that constitutes a
major health problem
with significant
comorbidities and a
considerable
associated
socioeconomic
burden.
Objective: To
describe the
clinical features
and management of
patients with NP
attending Spanish
allergy centers, the
use of health care
resources, and the
degree of compliance
with the diagnostic
and therapeutic
recommendations of
the European
Position Paper on
Rhinosinusitis and
Nasal Polyps (EPOS).
Methods: We
performed a
multicenter,
observational, and
cross-sectional
epidemiologic study
of 671 patients
consulting for NP in
67 Spanish allergy
departments. We used
sociodemographic and
clinical
questionnaires to
evaluate clinical
characteristics, use
of health care
resources,
diagnostic methods,
and treatment
administered.
Results: NP
was closely
associated with
asthma (66%),
allergic rhinitis
(45.9%), and
hypersensitivity to
nonsteroidal
anti-inflammatory
drugs (NSAIDs)
(26%). Atopy was
present in the 50%
of cases, with
Dermatophagoides
pteronyssinus as
the most frequent
sensitizing
allergen. Eleven
percent of NP
patients visited the
emergency department
during the previous
year, and more than
58% used primary
care, allergy, or
otorhinolaryngology
services. The most
frequently used
diagnostic tests
were skin prick
tests (93.6%) and
anterior rhinoscopy
(79.4%). Intranasal
corticosteroids were
the drug class most
frequently
prescribed by
allergists (74.6%).
Specific
immunotherapy was
prescribed in 21% of
patients.
Conclusions:
NP is a chronic
inflammatory disease
that generates
considerable use of
health care
resources. The close
association with
atopy, asthma, and
NSAID
hypersensitivity
highlights the
usefulness of an
allergy workup in
all patients with
NP. Analysis of the
clinical management
of NP by allergists
in Spain revealed a
high degree of
compliance with EPOS
diagnostic and
therapeutic
recommendations.
Key words:
Allergological
evaluation. Atopy.
Health care
resources. Nasal
polyps. Diagnosis.
Treatment. |
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