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Validation of the Spanish Version of the Food Allergy Quality of Life Questionnaire-Parent Form (S-FAQLQ-PF)

Manso L1, Pineda R1, Huertas B1, Fernández-Rivas M2, Diéguez MC3, Cerecedo I2, Muriel A4, Fernández FB5, DunnGalvin A6, Antolín-Amérigo D7, De la Hoz B8

1Sección de Alergología, Hospital Universitario del Sureste, Arganda del Rey (Madrid), Spain
2Servicio de Alergia, Hospital Universitario Clínico San Carlos, Madrid, Spain
3Servicio de Alergia, Hospital Universitario 12 de Octubre, Madrid, Spain
4Ramón y Cajal Hospital, IRYCIS; CIBER de Epidemiología y Salud Pública (CIBERESP), Universidad Autónoma de Madrid; Facultad de Económicas y Administración de Empresas, Departamento de Economía Aplicada, Madrid, Spain
5Unidad de Bioestadística, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
6Department of Paediatrics and Child Health Clinical Investigations Unit, Cork University Hospital, Wilton, Cork, Ireland
7Servicio de Enfermedades del Sistema Inmune-Alergia, Hospital Universitario Príncipe de Asturias, Alcalá de Henares (Madrid), Spain
8Servicio de Alergia, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain

J Investig Allergol Clin Immunol 2017; Vol 27(6) : 363-369
doi: 10.18176/jiaci.0182

Background: Food allergy is an emerging health problem. Several questionnaires can be used to establish health-related quality of life (HRQOL) in food allergy patients. Current questionnaires should be translated in such a way that they take account of the culture of the country in which they are to be used.
Objective: To translate and perform a cross-sectional validation of the Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF).
Methods: The parents of 54 children diagnosed with food allergy were recruited to assess the Spanish version of the FAQLQ-PF (S-FQLQ-PF).
Results: The S-FQLQ-PF was translated into Spanish according to WHO guidelines (including a forward-backward translation). The statistical analysis showed that feasibility, reliability, and internal consistency were very good for the global S-FAQLQ-PF score and for the different domains. Assessment of construct validity indicated that S-FAQLQ-PF has reduced capacity for measurement of HRQOL in younger children. Cross-sectional validation of the S-FAQLQ-PF demonstrated that HRQOL of a Spanish pediatric population was affected by patient age, severity of symptoms, and number of reactions. HRQOL was not affected by sex, food implicated, number of foods implicated, ingestion of the implicated food, or presence of anaphylaxis.
Conclusion: Translation into Spanish and cultural validation of the FAQLQ-PF demonstrated the influence of factors, such as patient age, severity of symptoms, and number of reactions on the HRQOL of a pediatric Spanish population.

Key words: Allergy, Food allergy, Quality of life, Questionnaire, Spanish, Validation.