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Objective:
This study aimed to
evaluate the adverse
effects of
extensively
hydrolyzed milk
formula on growth in
infants and toddlers.
Methods:
Prospectively, 45
infants and toddlers
with a positive
history of cows
milk allergy
confirmed by
positive skin prick
test and high IgE
levels for either α-lactalbumin,
ß-lactoglobulin, or
casein and positive
single-blind food
challenge received
extensively
hydrolyzed milk
formulas for 1 year.
Sex-normalized
percentiles of
heights and weights
of infants and
toddlers before
their enrollment in
the study were
compared to those at
the end of the study.
The contribution of
breastfeeding, early
use of bottle
feeding and intake
of adapted or
special milk
formulas, and
history of
bronchitis and
atopic dermatitis on
toddlers growth
were also evaluated
by multivariate
analysis.
Results:
Similar percentiles
of the childrens
weight and height
were observed at the
beginning of the
study and 1 year
later. According to
the multivariate
analysis, sex,
breastfeeding, early
bottle feeding,
ingestion of adapted
or special milk
formulas, atopic
dermatitis, and
bronchitis were not
correlated with
either the
childrens weight or
height at diagnosis
of the allergy or at
1 year of follow-up
(P > .10). Weights
and heights were not
different between
toddlers who had
atopic dermatitis or
bronchitis during
the study period and
those who did not.
Conclusions:
Growth of infants
and toddlers with
cows milk allergy
was not affected by
the intake of
extensively
hydrolyzed milk for
1 year. Atopic
dermatitis and
bronchitis did not
appear to have any
deleterious effect
on these childrens
growth.
Key words:
Body measures. Food
hypersensitivity.
Postnatal growth. |
