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Neutrophils and Asthma


J Monteseirín

Immunology and Allergy Service, University Hospital Virgen Macarena, Sevilla, Spain

J Investig Allergol Clin Immunol 2009; Vol. 19(5): 340-354



Although eosinophilic airway inflammation is recognized as an important feature of some patients with chronic, stable asthma, evidence
supports an important role for neutrophils in asthma. Neutrophils are the first cells recruited to the site of the allergic reaction. Their
presence may influence clinical presentation and has been linked to the development of severe chronic asthma and sudden severe attacks.
Neutrophils are eliminated by apoptosis during the resolution of the allergic response.

Key words: Asthma. Neutrophil. Allergy. Eosinophil.