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Original Article


Quality of Life in Patients With Respiratory Allergy Is Influenced by the Causative Allergen


J Delgado,1* I Dávila,2* J Domínguez-Ortega,3 S Quirce,4 E Martí-Guadaño,5 A Valero6

1Allergy UGC, Hospital Virgen Macarena, Sevilla, Spain
2Immunoallergy Department, IBSAL-Hospital Universitario de Salamanca, Salamanca, Spain
3Allergy Unit, Hospital Universitario de Getafe, Getafe, Spain
4Allergy Department, Hospital La Paz Institute for Health Research (IdiPAZ), and CIBER de Enfermedades Respiratorias, CIBERES, Madrid, Spain
5Allergy Department, Hospital Moisès Broggi, Sant Joan Despí, Barcelona, Spain
6Pneumology and Allergy Department, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, Hospital Clínic, Barcelona, Spain
*Both authors contributed equally to this work

J Investig Allergol Clin Immunol 2013; Vol. 23(5): 309-314



Objective: We aimed to analyze health-related quality of life (HRQOL) in adults with newly diagnosed respiratory allergy according to the sensitization profile for relevant aeroallergens in their usual area of residence.

Methods: We performed a cross-sectional, epidemiological, observational, descriptive, multicenter study in allergy clinics in Spain. The sample comprised adults diagnosed with rhinitis, asthma, or both caused by significant allergens in their residential area (olive and/or grass pollen or house dust mite). Allergic rhinitis was classified according to the Allergic Rhinitis and its Impact on Asthma guidelines; asthma was classified according to the Guía Española para el Manejo del Asma (Spanish Guideline on the Management of Asthma). HRQOL was studied according to the ESPRINT-15 questionnaire and Mini Asthma Quality of Life Questionnaire. Control of asthma was measured using the Asthma Control Questionnaire 5.

Results: We studied 1437 patients. Rhinitis was the most common respiratory disease. The HRQOL of rhinitis patients was lower in those sensitized to olive pollen only and in those with combined sensitization to olive and grass pollens. HRQOL associated with rhinitis was worse in patients diagnosed with both rhinitis and asthma than in patients diagnosed with rhinitis only. Asthma patients sensitized to olive pollen or olive and grass pollens had worse HRQOL.

Conclusions: In our study population, the HRQOL of patients with respiratory allergies varied with the allergen responsible for symptoms. In patients with rhinitis, the presence of asthma significantly worsened rhinitis-associated HRQOL.

Key words: Cross-sectional. Epidemiological. Descriptive. Respiratory allergies. Health-related quality of life.