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Review

Action Plan to Reach the Global Availability of Adrenaline Auto-Injectors
Kase Tanno L, Demoly P, and on behalf of the Joint Allergy Academies
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0346
[summary] [PDF full-Text]

Common Variable Immunodeficiency: Epidemiology, Pathogenesis, Clinical manifestations, Diagnosis, Classification and Management
Yazdani R, Habibi S, Sharifi L, Azizi G, Abolhassani H, Olbrich P, Aghamohammadi A
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0388
[summary] [PDF full-Text]

What we know about fish allergy by the end of the decade?
Kourani E, Corazza F, Michel O, Doyen V
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0381
[summary] [PDF full-Text]

Diagnostic Approach for Suspected Allergic Cutaneous Reaction to a Permanent Tattoo
Silvestre JF, González-Villanueva I
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0383
[summary] [PDF full-Text]

Ebastine in the treatment of allergic rhinitis and urticaria: 30 years of clinical studies and real-world experience
Sastre J
J Investig Allergol Clin Immunol 2020; Vol. 30(3)
doi: 10.18176/jiaci.0401
[summary] [PDF full-Text]

Position Statement of the Spanish Society of Allergology and Clinical Immunology on Provocation Tests with Aspirin/Nonsteroidal anti-inflammatory drugs
Izquierdo Domínguez A, Bobolea I, Doña I, Campo P, Segura C, Ortega N, González R, Delgado J, Torres MJ, Dordal MT, and Behalf of the SEAIC Rhinoconjunctivitis Committee
J Investig Allergol Clin Immunol 2020; Vol. 30(5)
doi: 10.18176/jiaci.0449
[summary] [PDF full-Text]

Guidelines

Referral criteria for asthma: Consensus document
Blanco Aparicio M, Delgado Romero J, Molina París J, Gómez Sáenz JT, Gómez Ruiz F, Álvarez Gutiérrez FJ, Domínguez Ortega J, Núñez Palomo S, Hidalgo Requena A, Vargas Ortega DA, Álvarez Puebla MJ, Carretero Gracia JA
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0393
[summary] [PDF full-Text]

Original Articles

VEGF -2549 -2567 del18 polymorphism and irreversible bronchoconstriction in asthmatics
Gomulka K, Liebhart J, Jaskula E, Lange A, Medrala W
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0369
[summary] [PDF full-Text]

IgE-mediated sensitization to galactose-alpha-1,3-galactose (a-gal) in urticaria and anaphylaxis in Spain: geographical variations and risk factors
Mateo-Borrega MB, Garcia B, Hernando Larramendi C, Azofra J, González-Mancebo E, Alvarado MI, Alonso Díaz de Durana MD, Núñez-Orjales R, Diéguez MC, Guilarte M, Soriano-Galarraga AM, Sosa G, Ferrer A, García-Moral A, Beristain AM, Bartra J
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0373
[summary] [PDF full-Text] [Supplemental Materials]

Incidence and risk factors of low-osmolar iodinated contrast media related immediate hypersensitivity reactions: A longitudinal study based on a real-time monitoring system
Suh-Young L, Dong Yoon K, Ju-Young K, Soon Ho Y, Young-Hoon C, Whal L, Sang Heon C, Hye-Ryun K
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0374
[summary] [PDF full-Text]

Relevance of Th2 markers in the assessment and therapeutic management of severe allergic asthma: a real life perspective
Caminati M, Vianello A, Chieco Bianchi F, Festi G, Guarnieri G, Marchi MR, Micheletto C, Olivieri M, Tognella S, Guerriero M, Senna G, NEONET Study Group
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0379
[summary] [PDF full-Text]

Clinical factors associated with the overuse of asthma rescue medication
Urrutia I, Delgado J, Domínguez-Ortega J, Mascarós E, Pérez M, Resler G, Plaza V, on behalf on the MISTRAL Investigators Group
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0387
[summary] [PDF full-Text]

Omalizumab’s effectiveness in severe allergic asthma and nasal polyps: a real-life study
Tiotiu A, Oster JP, Roux P, Nguyen Thi PL, Peiffer G, Bonniaud P, Dalphin JC, de Blay F
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0391
[summary] [PDF full-Text]

General anesthetics drug challenge tests: predictive value of skin tests
Tornero Molina P, Rojas-Perez-Ezquerra P, Noguerado-Mellado B, Baeza Ochoa de Ocáriz ML, Garrido Sánchez A, Alonso Mateos M, Zubeldia Ortuño JM
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0402
[summary] [PDF full-Text] [Supplemental Materials]

Promoter genotyping and mRNA expression analysis of PTGDR gene in allergy
San Segundo-Val I, García-Sánchez A, Sanz C, Cornejo-García JA, Isidoro-García M, Dávila I
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0411
[summary] [PDF full-Text] [Supplemental Materials]

Atopic dermatitis phenotypes in preschool and school-age children: a latent class analysis
Galli E, Maiello N, Cipriani F, La Grutta S, Fasola S, Carello R, Caminiti L, Licari A, Landi M, Di Mauro D, Ricci G, Panel of the Italian Society of Pediatric Allergy and Immunology (SIAIP)
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0409
[summary] [PDF full-Text] [Supplemental Materials]

Subcutaneous immunotherapy with high-dose cat and dog extracts: a real-life study
Uriarte SA, Sastre J
J Investig Allergol Clin Immunol 2020; Vol. 30(3)
doi: 10.18176/jiaci.0415
[summary] [PDF full-Text]

Adaptation to Spanish and validation of the Rhinitis Control Assessment Test (RCAT) questionnaire
Del Cuvillo A, Sastre J, Colás C, Navarro AM, Mullol J, Valero A
J Investig Allergol Clin Immunol 2020; Vol. 30(3)
doi: 10.18176/jiaci.0420
[summary] [PDF full-Text]

FOXP3 expression, vitamins D and C in the prediction of tolerance acquisition in infants with cow’s milk allergy
Sardecka I, Łoś-Rycharska E, Gawryjołek J, Toporowska – Kowalska E, Krogulska A
J Investig Allergol Clin Immunol 2020; Vol. 30(3)
doi: 10.18176/jiaci.0422
[summary] [PDF full-Text] [Supplemental Materials]

Does Rapid Drug Desensitization to chemotherapy affect survival outcomes?
Berges-Gimeno MP, Carpio-Escalona LV, Longo-Muñoz F, Bernal-Rubio L, Lopez-Gonzalez P, Gehlhaar P, Pachon V, Ferreiro-Monteagudo R, Madrigal-Burgaleta R, Alvarez-Cuesta E
J Investig Allergol Clin Immunol 2020; Vol. 30(4)
doi: 10.18176/jiaci.0425
[summary] [PDF full-Text]

Main contributory factors on asthma control and health-related quality of life (QoL) in elderly asthmatics
Enríquez-Matas A, Fernández Rodríguez C, Andrés Esteban EM, Fernández Crespo J
J Investig Allergol Clin Immunol 2020; Vol. 30(4)
doi: 10.18176/jiaci.0430
[summary] [PDF full-Text]

Molecular diagnosis in house dust mite allergic patients suggests clinical relevance of Der p 23 in asthmatic children
Jiménez-Feijoo R, Pascal M, Moya R, Riggioni C, Domínguez O, Lózano J, Álvaro-Lozano M, Piquert M, Machinena A, Folque M, Dias M, Carnés J, Plaza AM
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0431
[summary] [PDF full-Text]

The safety and efficacy of aspirin desensitization combined with long-term aspirin therapy in Aspirin-exacerbated respiratory disease
Renjiao L, Fengming L
J Investig Allergol Clin Immunol 2020; Vol. 30(5)
doi: 10.18176/jiaci.0433
[summary] [PDF full-Text]

Immunochemical and physical quantitation of grass and olive pollen allergens and correlation with asthma admitions in Cáceres, Spain
Porcel Carreño S, Gómez Nieves E, Fernández-Caldas E, Abel Fernández E, Cases B, Tudela JI, Maghfour Martin Y, Domínguez Domínguez E, Alvarado Arenas M, Jiménez Timón S, Ahmida T, García Ponce JF, Jiménez Gallardo P, Alvarado Izquierdo MI, Hernández Arbeiza J
J Investig Allergol Clin Immunol 2020; Vol. 30(5)
doi: 10.18176/jiaci.0434
[summary] [PDF full-Text]

Contribution of recombinant Parvalbumin Gad c 1 in the diagnosis and prognosis of fish allergy
Carvalho S, Marcelino J, Cabral Duarte M, Costa C, Barbosa M, Pereira Dos Santos MC
J Investig Allergol Clin Immunol 2020; Vol. 30(5)
doi: 10.18176/jiaci.0437
[summary] [PDF full-Text]

Molecular allergen profiling of dual mite sensitization in severe allergic rhinitis
González-Pérez R, Pineda F, Poza-Guedes P, Castillo M, Matheu V, Sánchez-Machín I
J Investig Allergol Clin Immunol 2020; Vol. 30(6)
doi: 10.18176/jiaci.0439
[summary] [PDF full-Text]

Quality of Life and characterization of patients with atopic dermatitis in Portugal - QUADEP study
Carvalho D, Aguiar P, Mendes-Bastos P, Palma-Carlos A, Freitas J, Ferrinho P
J Investig Allergol Clin Immunol 2020; Vol. 30(6)
doi: 10.18176/jiaci.0443
[summary] [PDF full-Text]

Paediatric Barcelona Olfactory Test-6 (pBOT-6): Validation of a Combined Odour Identification and Threshold Screening Test in Healthy Spanish Children and Adolescents
Mariño-Sánchez F, Valls-Mateus M, Fragola C, de los Santos G, Aguirre A, Alonso J, Valero J, Santamaría A, Rojas Lechuga MJ, Cobeta I, Alobid I, Mullol J
J Investig Allergol Clin Immunol 2020; Vol. 30(6)
doi: 10.18176/jiaci.0451
[summary] [PDF full-Text]

Farm environment during pregnancy and childhood and polysensitization at the age of 31 - Prospective birth cohort study in Finland
Karvonen AM, Lampi J, Keski Nisula L, Auvinen J, Toppila Salmi S, Järvelin MR, Pekkanen J
J Investig Allergol Clin Immunol 2021; Vol. 31(1)
doi: 10.18176/jiaci.0455
[summary] [PDF full-Text] [Supplemental Materials]

A Comprehensive Prospective Study of Costs Associated to the Evaluation of beta-lactam Allergy
Sobrino García M, Muñoz Bellido FJ, Moreno E, Macías E, Gracia Bara MT, Laffond E, Lázaro Sastre M, Martín García C, de Arriba Méndez S, Campanón Toro MV, Gallardo Higueras A, Dávila I
J Investig Allergol Clin Immunol 2021; Vol. 31(1)
doi: 10.18176/jiaci.0457
[summary] [PDF full-Text] [Supplemental Materials]

Angiotensin-converting enzyme inhibitor-associated angioedema in a cohort of Caucasian patients: from bed to bench
Carucci L, Bova M, Petraroli A, Ferrara AL, Sutic A, de Crescenzo G, Cordisco G, Margaglione M, Gambardella J, Spadaro G, Genovese A, Loffredo S
J Investig Allergol Clin Immunol 2020; Vol. 30(4)
doi: 10.18176/jiaci.0458
[summary] [PDF full-Text]

Assessing Adherence by Combining the Test of Adherence to Inhalers with Pharmacy Refill Records
Plaza V, Giner J, Curto E, Alonso Ortiz MB, Orue MI, Vega JM, Cosío BG, Group of investigators of the RE-TAI study
J Investig Allergol Clin Immunol 2021; Vol. 31(1)
doi: 10.18176/jiaci.0461
[summary] [PDF full-Text] [Supplemental Materials]

Association between severity of anaphylaxis and coexistence of respiratory diseases: a systematic review and meta-analysis of observational studies
Farias-Aquino E, Tejedor-Alonso MA, Pérez-Fernández E, Moro-Moro M, Rosado-Ingelmo A, Alberti Masgrau N, Pérez-Codesido S, Privitera-Torres M
J Investig Allergol Clin Immunol 2021; Vol. 31(2)
doi: 10.18176/jiaci.0462
[summary] [PDF full-Text]

Practitioner’s Corner

Allergy to Spathiphyllum wallisii, an indoor allergen
Herrera-Lasso Regás V, Dalmau Duch G, Gázquez García V, Pineda De La Losa F, Castillo Fernández M, Garnica Velandia D, Gaig Jané P
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0419
[summary] [PDF full-Text]

Celiac disease and wheat allergy may coexist: two case reports
Lombardi C, Savi E, Passalacqua G
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0421
[summary] [PDF full-Text]

Survey of opinion of Spanish physicians on the role of eosinophils in asthma and other pathologies
Plaza V, Blanco M, Delgado J, Martínez I, Zubeldía JM, Molina J
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0423
[summary] [PDF full-Text] [Supplemental Materials]

Chronic Pulmonary Aspergillosis Succesfully Treated With Isavuconazole
Guillen-Vera D, Ruiz-Ruigómez M, García-Moguel I, Morales-Ruiz R, Corbella L, Fernández-Rodríguez C
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0424
[summary] [PDF full-Text] [Supplemental Materials]

Occupational asthma induced by quinoa exposure
Guarnieri G, Bonadonna P, Olivieri E, Schiappoli M
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0432
[summary] [PDF full-Text] [Supplemental Materials]

Chronic urticaria associated with occult papillary thyroid carcinoma and dramatic improvement after total thyroidectomy: A retrospective study from Turkey
Özkaya E, Kılıç Sayar S, Mahmudov A
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0435
[summary] [PDF full-Text]

Long-term remission of Wells syndrome with omalizumab
Coattrenec Y, Ibrahim LY, Harr T, Spoerl D, Jandus P
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0436
[summary] [PDF full-Text]

Eosinophilic esophagitis during latex desensitization
Nucera E, Urbani S, Buonomo A, Andriollo G, Aruanno A
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0440
[summary] [PDF full-Text]

Atopy can be an interfering factor in genetic association studies of beta-lactam allergy
Rivera Reigada ML, Moreno E, Sanz C, García-Sanchez A, Cornejo-García JA, Dávila I, Isidoro-García M
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0441
[summary] [PDF full-Text] [Supplemental Materials]

The method for selecting basophils might be determinant in the basophil activation test in patients with mastocytosis
Urra JM, Pérez Lucendo I, Extremera A, Feo Brito F, Alfaya T
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0442
[summary] [PDF full-Text]

Cypress pollen allergy in a Mediterranean area
Castillo Marchuet MJ, Luengo O, Cardona V
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0444
[summary] [PDF full-Text]

Rapid Drug Desensitization with Rituximab in 24 Cases: Single-Center Experience
Görgülü B, Cengiz Seval G, Kendirlinan R, Koçak Toprak S, Özcan M, Bavbek S
J Investig Allergol Clin Immunol 2019; Vol. 29(6)
doi: 10.18176/jiaci.0445
[summary] [PDF full-Text] [Supplemental Materials]

Occupational asthma and rhinitis due to yellow and red henna in a hairdresser
Villalobos V, Rial MJ, Pastor-Vargas C, Esteban I, Cuesta J, Sastre J
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0453
[summary] [PDF full-Text]

Multiple drug hypersensitivity syndrome to anti-TB drugs. A case report
Carneiro-Leão L, Gomes I, Freitas C, Costa e Silva M, Viseu R, Cernadas J
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0446
[summary] [PDF full-Text] [Supplemental Materials]

Asthma apps use and interest among patients with asthma: a multicentre study
Jácome C, Almeida R, Pereira AM, Araújo L, Correia M, Pereira M, Couto M, Lopes C, Chaves Loureiro C, Catarata MJ, Santos LM, Ramos B, Mendes A, Pedro E, Cidrais Rodrigues JC, Oliveira G, Aguiar AP, Arrobas AM, Costa J, Dias J, Todo Bom A, Azevedo J, Ribeiro C, Alves M, Leiria Pinto P, Neuparth N, Palhinha A, Gaspar Marques J, Martins P, Trincão D, Neves A, Todo Bom F, Alvarenga Santos M, Branco J, Lozoya C, Costa A, Silva Neto A, Silva D, Vasconcelos MJ, Teixeira MF, Ferreira-Magalhães M, Taborda Barata L, Carvalhal C, Santos N, Pinto CS, Rodrigues Alves R, Moreira AS, Morais Silva P, Fernandes R, Ferreira R, Alves C, Câmara R, Ferraz de Oliveira J, Bordalo D, Calix MJ, Marques A, Nunes C, Menezes F, Gomes R, Almeida Fonseca J, INSPIRERS group
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0456
[summary] [PDF full-Text] [Supplemental Materials]

Fatal anaphylactic shock induced by intravenous gelatin colloid: An allergological postmortem work-up
Molina Molina GJ, Carrasco González MD, Viñas Giménez L, Sanz Martínez M, Galván Blasco P, Luengo O, Guilarte M, Sala Cunill A, Cardona V, Labrador Horrillo M
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0459
[summary] [PDF full-Text]

Asthma, comorbidities, and aggravating circumstances. The GEMA-FORUM II task force
Trigueros JA, Plaza V, Domínguez Ortega J, Serrano J, Cisneros C, Padilla A, Antón Gironés M, Mosteiro M, Martínez Moragón E, Olaguíbel Rivera JM, Delgado J, García Rivero JL, Martínez Rivera C, Garrido JJ, Quirce S, GEMAFORUM task force
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0460
[summary] [PDF full-Text]

Tolerance to cephalosporins and carbapenems in penicillin allergic patients
Sánchez de Vicente J, Gamboa P, García-Lirio E, Irazabal B, Jáuregui I, Martínez MD, Segurola A, Seras Y, Galán C
J Investig Allergol Clin Immunol 2020; Vol. 30(1)
doi: 10.18176/jiaci.0463
[summary] [PDF full-Text]

H1-antihistamines may be no longer necessary for patients with refractory chronic spontaneous urticaria after introduction of omalizumab treatment
Ensina LF, Arruda LK, Campos RA, Criado RFJ, Valle SOR, Melo JML, Oliveira JCS, Dortas-Junior SD, Cusato Ensina AP, Camelo Nunes IC, Agondi RC
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0464
[summary] [PDF full-Text] [Supplemental Materials]

Desquamating-nonpigmenting with onycholysis fixed drug eruption in a child due to amoxicillin. Cross-reactivity study
Moya B, Vera A, Bazire R, Betancor D, Rodríguez Del Río P, Escudero C, Ibáñez MD
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0466
[summary] [PDF full-Text]

A new terminal nonsense mutation of Cathepsin C gene in a patient with atypical Papillon-Lefèvre Syndrome
Moura AL, Regateiro FS, Peres Resende E, Gonçalo M, Todo Bom A, Faria E
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0467
[summary] [PDF full-Text]

Exhaled nitric oxide (eNO) measurements with the new evernoa® device, through a extended range of eNO levels, are valid and reproducible
Olaguibel A, Oleaga M, Iraola A, Cortaberría R, Corcuera A, Álvarez Puebla MJ, Tabar A, Ruete L, Botas A, Olaguibel JM
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0465
[summary] [PDF full-Text] [Supplemental Materials]

Long-Term Anti-Interleukin 5 Antibodies Treatment in a Patient with Chronic Eosinophilic Pneumonia
Shimizu Y, Kurosawa M, Sutoh Y, Sutoh E
J Investig Allergol Clin Immunol 2020; Vol. 30(2)
doi: 10.18176/jiaci.0468
[summary] [PDF full-Text] [Supplemental Materials]