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Review

Clinical Approach to Mast Cell Activation Syndromes: A Practical Overview
Matito A, Escribese MM, Longo N, Mayorga C, Luengo-Sánchez O, Pérez-Gordo M, Matheu V, Labrador-Horrillo M, Pascal M, Seoane-Reula ME, on behalf of the Comité de Inmunología de la Sociedad Española de Alergología e Inmunología Clínica (SEAIC)
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0675
[summary] [PDF full-Text]

Dupilumab: a Review of Present Indications and Uses Out Of Indication
Muñoz-Bellido FJ, Moreno E, Dávila I
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0682
[summary] [PDF full-Text]

Treatment and outcome in deficiency of adenosine deaminase 2: a literature review
Zhang B, Xu N, Chen J, Zhang S, Huang X, Shen M, Zeng X
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0748
[summary] [PDF full-Text] [Supplemental Materials]

FAQS on when to use Molecular Allergy Diagnosis (MD) in clinical practice
Luengo O, Labrador-Horrillo M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0769
[summary] [PDF full-Text]

Original Articles

Direct costs of Acute Rhinosinusitis in Spain - a prospective and observational study (PROSINUS)
Jaume F, Quintó LL, Alobid I, Mullol J
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0525
[summary] [PDF full-Text]

Factors associated with asthma control in 121 preschool children
Leiria-Pinto P, Carreiro-Martins P, Peralta I, Marques J, Finelli E, Alves C, Belo J, Alves M, Papoila AL, Neuparth N
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0630
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis: a decade of a nationwide allergy society registry
Gaspar A, Santos N, Faria E, Câmara R, Rodrigues-Alves R, Carrapatoso I, Gomes E, Pereira AM, Carneiro-Leão L, Morais-Almeida M, Delgado L, Pedro E, Branco-Ferreira M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0515
[summary] [PDF full-Text]

Molecular Sensitization Profile to Dermatophagoides pteronyssinus Dust Mite in Portugal
Limão R, Spínola Santos A, Araújo L, Cosme J, Inácio F, Tomaz E, Ferrão A, Santos N, Sokolova A, Môrete A, Falcão H, Cunha L, Ferreira A, Bras A, Ribeiro F, Lozoya C, Leiria Pinto P, Prates S, Plácido J, Coimbra A, Taborda-Barata L, Pereira Santos MC, Pereira Barbosa M, Pineda F
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0533
[summary] [PDF full-Text]

Detection of Gibberellin-Regulated Protein (Peamaclein) Sensitization among Italian Cypress Pollen-Sensitized Patients
Asero R, Abbadessa S, Aruanno A, Barilaro G, Barzaghi C, Bignardi D, Bilò MB, Borro M, Bresciani M, Busa M, Buzzulini F, Cavaliere C, Cecchi L, Ciccarelli A, Cortellini G, Cucinelli F, Deleonardi G, Emiliani F, Farsi A, Ferrarini E, Franchini M, Ingrassia A, Lippolis D, Losappio L, Marra AM, Martini M, Masieri S, Mauro M, Mazzolini M, Muratore L, Murzilli F, Nucera E, Pastorello EA, Pinter E, Polillo BR, Pravettoni V, Quercia O, Rizzi A, Russello M, Sacerdoti C, Scala E, Scala G, Scarpa A, Schroeder J, Uasuf GG, Villalta D, Yang B, Mistrello G, Amato S, Lidholm J
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0542
[summary] [PDF full-Text]

MRGPRX2 and Immediate Drug Hypersensitivity: Insights from Cultured Human Mast Cells
Elst J, Sabato V, Faber MA, Bridts CH, Mertens C, Van Houdt M, Van Gasse AL, Hagendorens MM, Van Tendeloo V, Maurer M, Campillo-Davo D, Timmermans JP, Pintelon I, Ebo DG
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0557
[summary] [PDF full-Text] [Supplemental Materials]

Api m 6 and Api m 10 as Major Allergens in Patients with Honeybee Venom Allergy
Vega-Castro A, Rodríguez-Gil D, Martínez-Gomariz M, Gallego R, Peña MI, Palacios R
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0639
[summary] [PDF full-Text] [Supplemental Materials]

Use of Dupilumab for 543 Adult Patients with Moderate-To-Severe Atopic Dermatitis: A Multicenter, Retrospective Study
Nettis E, Ferrucci SM, Ortoncelli M, Pellacani G, Foti C, Di Leo E, Patruno C, Rongioletti F, Argenziano G, Macchia L, Tavecchio S, Napolitano M, Ribero S, Bonzano L, Romita P, Di Bona D, Nisticò SP, Piras V, Calabrese G, Detoraki C, Carbonara M, Fabbrocini G
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0641
[summary] [PDF full-Text]

Clinical and immunologic changes due to subcutaneous immunotherapy with cat and dog extracts using an ultrarush up-dosing phase: a real-life study
Uriarte SA, Grönlund H, Wintersand A, Bronge J, Sastre J
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0656
[summary] [PDF full-Text] [Supplemental Materials]

A Specialized Therapeutic Approach to Chronic Urticaria Patient’s Refractory to H1-Antihistamines Improves the Burden of the Disease. The Spanish AWARE Experience
Gimenez-Arnau A, Bartra J, Ferrer M, Jauregui I, Borbujo J, Figueras I, Muñoz-Bellido FJ, Pedraz J, Serra-Baldrich E, Tejedor-Alonso MA, Velasco M, Terradas P, Labrador M
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0661
[summary] [PDF full-Text] [Supplemental Materials]

Unraveling Kiwifruit Allergy Diagnosis: Usefulness of the Current Diagnostic Tests
D’Amelio CM, Bernad A, García-Figueroa BE, Garrido-Fernández S, Azofra J, Beristain A, Bueno-Díaz C, Garrido-Arandia M, Gastaminza G, Ferrer M, Díaz Perales A, Villalba M, Goikoetxea MJ
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0691
[summary] [PDF full-Text] [Supplemental Materials]

Budget impact analysis of Fractional Exhaled Nitric Oxide Monitoring for the Management of Childhood Asthma: The Colombian National Health System perspective
Buendía JA, Acuña-Cordero R, Rodriguez-Martinez CE
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0690
[summary] [PDF full-Text]

Incidence of Fatal Anaphylaxis: A Systematic Review of Observational Studies
Perez-Codesido S, Rosado-Ingelmo A, Privitera-Torres M, Pérez Fernández E, Nieto-Nieto A, Gonzalez-Moreno A, Grifol-Clar E, Alberti-Masgrau N, Tejedor-Alonso MA
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0693
[summary] [PDF full-Text] [Supplemental Materials]

Onset of nut allergy in a pediatric cohort: clinical and molecular patterns. AFRUSEN study
Ibáñez-Sandin MD, Rodríguez del Río P, Alvarado MI, García BE, Garriga-Baraut T, Reche Frutos M, Escudero C, Ramirez A, Vila L, Lasa EM, Blasco C, Marchán-Martin E, Martorell A, Sanchez-García S, Rodríguez-Álvarez M, Infante S, Rodríguez Vazquez V, Olaguibel JM, Labrador-Horrillo M, Carrillo T, AFRUSEN task force, Pediatric Allergy Committee, Spanish Society of Allergy and Clinical Immunology (SEAIC)
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0696
[summary] [PDF full-Text] [Supplemental Materials]

Risk Factors in Severe Anaphylaxis: Which Matters The Most, Food or Cofactors?
Casas-Saucedo R, de la Cruz C, Araujo-Sánchez G, Gelis S, Jimenez T, Riggioni S, San Bartolomé C, Pascal M, Bartra Tomás J, Muñoz-Cano R
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0698
[summary] [PDF full-Text] [Supplemental Materials]

Allergen Profile of London Plane Tree Pollen: Clinical and Molecular Pattern in Central Spain
Nuñez-Borque E, Betancor D, Fernández-Bravo S, Gómez-Cardeñosa A, Esteban V, Garrido-Arandia M, de las Heras M, Pastor-Vargas C, Cuesta-Herranz J
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0702
[summary] [PDF full-Text]

Seed Storage Proteins, 2S Albumin And 11S Globulin, Associated to Severe Allergic Reactions after Flaxseed Intake
Bueno-Díaz C, Biserni C, Martín-Pedraza L, de las Heras M, Blanco C, Vázquez-Cortés S, Fernández-Rivas M, Batanero E, Cuesta-Herranz J, Villalba M
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0713
[summary] [PDF full-Text] [Supplemental Materials]

Helios negative Regulatory T-cells as a key factor of immune tolerance in non-allergic beekeepers
Ruiz-Leon B, Navas A, Serrano P, Espinazo M, Guler I, Alonso C, Jurado A, Moreno-Aguilar C
J Investig Allergol Clin Immunol 2022; Vol. 32(6)
doi: 10.18176/jiaci.0722
[summary] [PDF full-Text] [Supplemental Materials]

Atopic Dermatitis Patients with Pet Dander Sensitization Mount IgE and T cell Responses to Mammalian Cystatins Including the Human Self-Protein
Roesner LM, Swiontek K, Lentz D, Begemann G, Kienlin P, Hentges F, Ollert M, Werfel T, Hilger C
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0737
[summary] [PDF full-Text] [Supplemental Materials]

Usefulness of the Allergen Specific Nasal Provocation Test in the Diagnosis of Shellfish Allergy
Gelis S, Rueda M, Pascal M, Fernández-Caldas E, Abel Fernández E, Araujo-Sánchez G, Bartra J, Valero A
J Investig Allergol Clin Immunol 2022; Vol. 32(6)
doi: 10.18176/jiaci.0736
[summary] [PDF full-Text] [Supplemental Materials]

Serum microRNAs catalog asthmatic patients by phenotype
Gil-Martínez M, Rodrigo-Muñoz JM, Sastre B, Cañas JA, García-Latorre R, Redondo N, de la Fuente L, Mínguez P, Mahíllo-Fernández I, Sastre J, Quirce S, Caballero ML, Olaguibel JM, Pozo V
J Investig Allergol Clin Immunol 2022; Vol. 32(6)
doi: 10.18176/jiaci.0753
[summary] [PDF full-Text] [Supplemental Materials]

Clinical and immunological characterization of perilla seed allergy in children
Jeong K, Lee SY, Jeon SA, Gantulga P, Nam JY, Hong SJ, Lee S
J Investig Allergol Clin Immunol 2023; Vol. 33(1)
doi: 10.18176/jiaci.0756
[summary] [PDF full-Text] [Supplemental Materials]

Sex differences in baseline risk factors for the incidence of asthma between early adolescence and young adulthood
Kalm-Stephens P, Nordvall L, Janson C, Malinovschi A, Alving K
J Investig Allergol Clin Immunol 2022; Vol. 33(1)
doi: 10.18176/jiaci.0763
[summary] [PDF full-Text] [Supplemental Materials]

Systemic Corticosteroids in Patients with Bronchial Asthma: A Real-Life Study
Izquierdo JL, Almonacid C, Campos C, Morena D, Benavent M, González-de-Olano D, Rodríguez JM
J Investig Allergol Clin Immunol 2022; Vol. 33(1)
doi: 10.18176/jiaci.0765
[summary] [PDF full-Text] [Supplemental Materials]

Economic consequences of the overuse of short-acting beta-adrenergic agonists (SABA) in the treatment of asthma in Spain
Valero A, Molina J, Nuevo J, Simon S, Capel M, Sicras-Mainar A, Sicras-Navarro A, Plaza V
J Investig Allergol Clin Immunol 2022; Vol. 33(2)
doi: 10.18176/jiaci.0767
[summary] [PDF full-Text] [Supplemental Materials]

Atopic manifestations are underestimated clinical features in various primary immunodeficiency disease phenotypes
de Wit J, Dalm V, Totté JEE, Kamphuis LSJ, Vermont CL, van Osnabrugge FY, van Hagen PM, Pasmans SGMA
J Investig Allergol Clin Immunol 2022; Vol. 33(2)
doi: 10.18176/jiaci.0768
[summary] [PDF full-Text] [Supplemental Materials]

Practitioner's Corner

Short Communications

Where Have All The Nasal Polyposis Gone?
Ortega-Martin L, Betancor D, Barroso B, Valverde-Monge M, Santillan J, Villacampa JM, Sastre J
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0679
[summary] [PDF full-Text]

Large Local Reactions to Hymenoptera Stings Negatively Affect Quality Of Life to the Same Degree as Systemic Reactions
Sánchez-Morillas L, Alfaya Arias T, Martínez San Ireneo M, Domínguez Noche C, Vega Gutierrez JM, Vega Castro A, Moreno Mata E, Marqués L, Fuentes Ferrer M, Ruiz-León B, Hymenoptera Allergy Committee of the SEAIC
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0688
[summary] [PDF full-Text] [Supplemental Materials]

Patterns of Cross-Reactivity in Patients with Immediate Hypersensitivity Reactions to Gadobrutol
Gallardo-Higueras A, Moreno EM, Muñoz-Bellido FJ, Laffond ELaffond , Gracia-Bara MT, Macias EM, Campanon MV, de Arriba S, Martin C, Sobrino M, Davila I
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0694
[summary] [PDF full-Text]

Circulating Epithelial Cell Cytokines Are Associated With Early Onset Atopic Dermatitis
Gamez C, Metcalfe J, Prescott SL, Palmer DJ
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0699
[summary] [PDF full-Text] [Supplemental Materials]

Consistency of sIgE Determination and Basophil Activation Test in Vespa velutina nigrithorax Allergy
Rodríguez-Vázquez V, Gómez-Rial J, Monsalve RI, Vidal C
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0716
[summary] [PDF full-Text] [Supplemental Materials]

Administration of the Comirnaty® Vaccine in a Fractional Regimen in Two Patients with Immediate Acute Urticaria after the First Dose
Antón Gironés M, Montoro Lacomba j, Navarro Cascales T, Lindo Gutarra M, Marco de la Calle FM
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0717
[summary] [PDF full-Text] [Supplemental Materials]

Immediate-Type Hypersensitivity to Polyethylene Glycol (PEG) Including a PEG-containing COVID-19 Vaccine Revealed by Intradermal Testing
Pickert J, Hennighausen I, Mühlenbein S, Möbs C, Pfützner W
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0720
[summary] [PDF full-Text] [Supplemental Materials]

B cells and COVID-19: Lessons from agammaglobulinemia patients and the study of functional B cell polymorphisms
Speletas M, Raftopoulou S, Farmaki E, Gatselis N, Germanidis G, Mouchtouri V, Hatzianastasiou S, Georgiadou S, Tsinti G, Tsachouridou O, Tseroni M, Metallidis S, Dalekos G, Eibel H, Hadjichristodoulou C
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0726
[summary] [PDF full-Text]

Findings in Chest High-Resolution Computed Tomography in Severe Asthma
Extremera Ortega AM, Moreno Lozano L, González Jiménez OM, Borja Segade J, Joyanes Romo JB, Muñoz Rodríguez JR, Feo-Brito F, Galindo Bonilla PA
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0725
[summary] [PDF full-Text] [Supplemental Materials]

Drug hypersensitivity in cutaneous manifestations of SARS-CoV-2 infected patients
Solano-Solares E, Chica-Guzmán V, Pérez-Allegue I, Cabrera-Hernández R, Fernández-Guarino M, Fernández-Nieto D, de-la-Hoz-Caballer B, González-de-Olano D, García-Bermejo L, de-Andres-Martin A, Moreno-García-del-Real C
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0744
[summary] [PDF full-Text] [Supplemental Materials]

Allergic reactions after administration of pfizer-biontech covid-19 vaccine to healthcare workers at a tertiary hospital
Loli-Ausejo D, González de Abreu JM, Fiandor A, Cabañas R, Domínguez-Ortega J, Caballero ML, Lluch-Bernal M, Rodrigo García-Panto C, Núñez MC, Quirce S
J Investig Allergol Clin Immunol 2022; Vol. 31(6)
doi: 10.18176/jiaci.0751
[summary] [PDF full-Text] [Supplemental Materials]

Exploring adherence to treatment in nasal polyposis
Valverde-Monge M, Barroso B, Ortega-Martin L, Betancor D, Santillan J, Villacampa JM, Sastre J
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0752
[summary] [PDF full-Text]

Sensitization profile to related animal proteins (crocodile, frog, and chicken) among fish-allergic patients
Haroun-Díaz E, Blanca-López N, Martín-Pedraza L, Ruano FJ, Somoza ML, Vázquez de la Torre M, Pérez-Alzate D, López-González P, Prieto-Moreno A, Bartolomé B, Blanca M, Canto G
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0705
[summary] [PDF full-Text] [Supplemental Materials]

Cluster sub-analysis of patients with severe asthma who responded to omalizumab
Dávila I, Campo P, Cimbollek S, Almonacid Sánchez C, Quirce S, Moreira A, Ramirez A, Soto Campos G
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0731
[summary] [PDF full-Text] [Supplemental Materials]

Nonasthmatic Eosinophilic Bronchitis and Asthma Development: analysis of biomarkers
Villalobos-Violan V, Betancor D, Mahíllo-Fernández I, Sastre J
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0738
[summary] [PDF full-Text] [Supplemental Materials]

Evaluation of fractional exhaled nitric oxide during SARS-CoV-2 infection
Betancor D, Valverde-Mongue M, Gomez-Lopez A, Barroso B, Ruete L, Olaguibel JM, Sastre J
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0762
[summary] [PDF full-Text] [Supplemental Materials]

Case Reports

Severe Anaphylaxis on Murine Antibodies in Sulesomab
Jacobs J, Coorevits L, Verscuren R, Frans G, Schrijvers R, Breynaert C
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0676
[summary] [PDF full-Text] [Supplemental Materials]

Successful Desensitization to Daratumumab after Severe Life-Threatening Reaction in A Patient with Refractory Multiple Myeloma
Carrón-Herrero A, Solano-Solares E, Rita CG, Rodríguez-Martín E, Berges-Gimeno MP, Ruedas A, Barbolla I
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0678
[summary] [PDF full-Text]

Unusual Secretion of Eosinophil Mediators Induced by Benralizumab
Cañas JA, Valverde-Monge M, Rodríguez-Nieto MJ, González-Mangado N, Sastre J, del Pozo V
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0684
[summary] [PDF full-Text] [Supplemental Materials]

First Case of Symmetric Drug-Related Intertriginous and Flexural Exanthema Induced by Meropenem
Blanco Garcia-Granero D, Barranco R, García-Moguel I, Velasco V, Diéguez Pastor MC
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0685
[summary] [PDF full-Text] [Supplemental Materials]

Neutrophilic Generalized Fixed Drug Eruption Induced By Etoricoxib
Vera A, Freih A, Múgica MV, Vega F, Belver MT, Blanco C
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0687
[summary] [PDF full-Text] [Supplemental Materials]

Benralizumab: Blowing Out Eosinophilic Pulmonary Vasculitis in A EGPA Patient
Bormioli S, Vultaggio A, Nencini F, Comin CE, Bercich L, Bezzi M, Vivarelli E, Calosi L, Chiccoli F, Matucci A
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0689
[summary] [PDF full-Text] [Supplemental Materials]

COVID-19 and TEN treated with IVIG and Total plasma exchange. Simultaneous systemic treatment for both diseases
Krajewski A, Mlynska-Krajewska E, Kaczynska K, Strużyna J, Mazurek MJ
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0692
[summary] [PDF full-Text]

Ascites as a Rare Presentation of Eosinophilic Enteritis in a Pollinic Patient
López-Sáez MP, Magdalena Betencourt K, Muñoz Tornero M, Alajarin Cervera M, Serrano Santos E, Sánchez-Guerrero Villajos I, López Sánchez D
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0697
[summary] [PDF full-Text]

Identification of Ribosomal Proteins as Cross-Reactive Allergens in a Case of Mushroom Food Allergy
Ogino R, Chinuki Y, Tobita R, Morita E
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0700
[summary] [PDF full-Text] [Supplemental Materials]

Allergic Rhinitis Due To the Ornamental Plant Sansevieria Trifasciata
Nin-Valencia A, Tomás-Pérez M, Bartolomé Zavala B
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0704
[summary] [PDF full-Text]

Immediate Hypersensitivity to Mealworm and Cricket: Beyond Shrimp and House Dust Mite Cross Reactivity
Mankouri F, Sereme Y, Michel M, Piarroux R, Pahus L, Chanez P, Vitte J, Gouitaa M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0707
[summary] [PDF full-Text] [Supplemental Materials]

Management of Hypersensitivity to Trimethoprim-Sulfamethoxazole with Ultra-Rapid Desensitization Protocol in HIV Infection
Villarreal-Gonzalez RV, Gonzalez-Diaz SN, Canel Paredes A, De Lira-Quezada CE, Rocha-Silva GK, López Méndez A
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0708
[summary] [PDF full-Text]

Acute Localized Exanthematouspustulosis Due to Alendronate
Bautista-Villanueva S, Galleani C, Barranco R, Bellón T, Blanco M, García-Moguel I
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0709
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis to Sunflower Seed with Tolerance to Other Nuts. The Role of Lipophilic Allergens
González-Bravo L, Laiseca-García J, Pineda F, Rosado A
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0710
[summary] [PDF full-Text]

Custard Apple Allergy with Glycosyltransferase as the Allergen Involved
Carrón-Herrero A, Fernández-Lozano C, Peracho L, Martínez-Alonso E, Alcázar A, Martínez-Botas J, de-La-Hoz-Caballer B, González-de-Olano D
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0711
[summary] [PDF full-Text]

Exacerbation Rate Reduction with Mepolizumab, Stratified by Maintenance OCS Use and Eosinophil Levels. A Post-Hoc Analysis of DREAM and MENSA Studies
Bobolea I, Bañas D, Melero C, de Andrés AI, Joksaite S, Sánchez-Herrero G
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0714
[summary] [PDF full-Text]

Anaphylaxis Due to Silene Vulgaris Ingestion
Haroun-Díaz E, Torres I, Blanca-López N, Somoza ML, Martín-Pedraza L, Ruano FJ, Vázquez de la Torre M, Cuesta-Herranz J, Bartolomé Zavala B, Blanca M, Canto Díez G
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0715
[summary] [PDF full-Text]

Hypersensitivity to COVID-19 Vaccine Confirmed by a Positive Skin Test Result: A Case Report
Pérez-Codesido S, Rosado A, Alonso-Díaz-de-Durana MD, Alfaya Arias T, González-Moreno A, Tejedor Alonso MA
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0718
[summary] [PDF full-Text] [Supplemental Materials]

Sugammadex Induced Anaphylaxis: Two Case Reports
Lazo Uslar C, Navarro Vives L, Miquel Marco S, Roger Reig A, Basagaña Torrento M
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0719
[summary] [PDF full-Text]

Kounis syndrome in a Covid-19 patient following intravenous azithromycin administration
Gogos C, Sachpekidis V, Moschovidis V, Styliadis I, Kounis NG
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0723
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis to goat’s and sheep’s milk in an adult tolerant to cow milk: A sensitization profile study
Hirsiger JR, Heijnen IAFM, Hartmann K, Berger CT
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0721
[summary] [PDF full-Text] [Supplemental Materials]

Caution against Temporary Tolerance and Negative Skin Testing During Anergic Period Following Systemic Reactions
Li P, Chiang V, Yeung HHF, Au EYL
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0724
[summary] [PDF full-Text]

DRESS Syndrome: Patch Testing As a Diagnostic Method That Brings Us Closer to a Certain Result
García-Paz V, González-Rivas M, Otero-Alonso A
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0728
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylactic Reactions with Three Non-Related Drugs (Gadoteridol, Paclitaxel, Bevacizumab) In a Patient with Severe Comorbidities
González-Bravo L, Laiseca García J, Alonso-Díaz-de-Durana MD, Nieto Nieto A, Álvarez-Twose I, Tejedor Alonso MA, Alfaya Arias T
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0729
[summary] [PDF full-Text]

Severe Perioperative Anaphylaxis Due to Allergy to the Sugammadex-Rocuronium Complex
Lopez-Raigada A, Vega de la Osada F, Lopez-Sanz C, Múgica García MV, Alfranca A, Blanco C
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0730
[summary] [PDF full-Text] [Supplemental Materials]

Polyethylene glycol allergy and immediate-type hypersensivitity reaction to COVID-19 vaccination: case report
Habran M, Vandebotermet M, Schrijvers R
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0740
[summary] [PDF full-Text] [Supplemental Materials]

Salt-dependent aquagenic urticaria, challenge test and histological features. Case report
Laiseca García J, Gónzalez Bravo L, Gomez de la Fuente E, Tristán Martin B, Sarró Fuentes C, Rosado A
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0735
[summary] [PDF full-Text]

Anaphylactic shock to Mediterranean silverside (Atherinaboyeri) caused by non-parvalbumin allergens
Giangrande N, García-Menaya JM, Bartolomé B, Fernández-Bolívar A, Cordobés-Durán C, Dotor-Lavado M, Marcos-Fernández M, Bobadilla-González P
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0732
[summary] [PDF full-Text]

Non-Immediate Maculopapular Erythema To Gadolinium-Based Contrast Agent
Gauthier A, Mankouri F, Demoly P, Chiriac AM
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0733
[summary] [PDF full-Text]

Anaphylactic shock following cataract surgery: a documented intracameral cefuroxime allergy
Mahiat C, Robaye S, Levecq L, Dumesnil D, Sohy C
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0741
[summary] [PDF full-Text]

Contact dermatitis from the glucose sensors: more than isobornyl acrylate (IBOA) allergy
Joyanes Romo JB, Borja Segade JM, Moreno Lozano L, García Rodríguez R, González Jiménez OM, Palacios Cañas A, Meneses Sotomayor JV, Gómez Torrijos E
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0739
[summary] [PDF full-Text]

Immunoglobulin g as milk allergen
Saura Foix MP, Bartolomé B, Barrena Crespo J, Delavalle B, Izquierdo Domínguez A, Hernández Arauzo N, Castillo Marchuet MJ, Viñas Domingo M
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0746
[summary] [PDF full-Text]

Pulmonary Geotrichosis in Chronic Granulomatous Disease
Palacios-Reyes D, Yamazaki-Nakashimada MA, Castaño-Jaramillo L, Roman-Montes CM, González-Lara MF, Scheffler-Mendoza S, Costta-Michuy A, Bustamante J, Blancas-Galicia L
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0749
[summary] [PDF full-Text] [Supplemental Materials]

Recurrent Salmonella Infections and Nephritis Complicating IgA Vasculitis in a Patient with IL12-RB1 Deficiency
Blancas-Galicia L, Peñafiel-Vicuña AK, Scheffler-Mendoza S, Rojas-Maruri M, Rivas-Larrauri F, Rodríguez-Lozano AL, Bustamante J, Yamazaki-Nakashimada MA
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0750
[summary] [PDF full-Text] [Supplemental Materials]

Viral-like reaction or hypersensitivity? Erythema multiforme minor reaction and moderate eosinophilia after receiving Pfizer-BioNTech BNT162b2 (mRNA-based SARS-CoV-2 vaccine)
de las Vecillas L, López J, Morchón E, Rodriguez F, Drake M, Martino M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0757
[summary] [PDF full-Text] [Supplemental Materials]

Millet seed sensitization in a lovebird keeper. A case report
Bravo E, González Mahave I, Sola JP, Vidal Oribe I, Hernández Alfonso P, Peñalver-Mellado M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0703
[summary] [PDF full-Text]

Multi-tool approach for high risk aspirin desensitization in a pregnant woman
Pérez Rodríguez E, Martínez Tadeo JA, Hernández Santana G, Iglesias Souto FJ, Rodríguez Plata E, Barrios Recio J, Callero Viera A
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0734
[summary] [PDF full-Text]

DRESS syndrome with gadolinium contrast media in a 13-year-old boy
Macías-Iglesias EM, Campanón-Toro MV, Moreno-Rodilla E, de Arriba-Méndez S, Sobrino-García M, Gallardo-Higueras A, Dávila González I
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0742
[summary] [PDF full-Text] [Supplemental Materials]

Allergy to beer and wine caused by Saccharomyces cerevisiae in a patient sensitized to fungi
German-Sanchez A, Alonso-Llamazares A, Garcia-Gonzalez F, Matala-Ahmed B, Bartolome-Zavala B, Antepara-Ercoreca I
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0755
[summary] [PDF full-Text]

Cutaneous B-cell lymphoma at the injection site of airborne allergen immunotherapy followed by cutaneous metastasis
Moreno Lozano L, Sánchez Caminero MP, García Arpa M, Mendez Díaz Y, Gonzalez Jiménez OM, Joyanes Romo JB, Palacios Cañas A, García Rodríguez R
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0758
[summary] [PDF full-Text] [Supplemental Materials]

Eosinophilic esophagitis caused by grass pollen sublingual immunotherapy with tolerance to a subcutaneous extract
Skrabski F, Pérez-Pallisé ME, Domínguez Estirado A, López Tovar C, Bermejo-Becerro A, Rodríguez Mazariego E, Zubeldia JM, Prieto García A
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0759
[summary] [PDF full-Text]

Desensitization to pertuzumab with positive skin test in a mixed phenotype hypersensitivity reaction
Lemus Calderón JA, Tapia de Pedro G, Marchan Martín E, Guzmán Rodríguez R, Cabañes Higuero MN, Senent Sánchez CJ
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0761
[summary] [PDF full-Text] [Supplemental Materials]

Generalized urticaria caused by glycerin enema in an infant
Kajita N, Kanamori K, Yamamoto S
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0760
[summary] [PDF full-Text]

Remifentanil-Induced Symmetric Drug-Related Intertriginous and Flexural Exanthema: A Diagnosis Challenge in an Intensive Care Patient
Martins JF, Coutinho IA, Castro M, Carvalho J, Faria C, Sousa E, Martins P
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0764
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis after mango fruit intake. Identification of new allergens
Ortega-Martín L, Sastre B, Rodrigo-Muñoz JM, Cañas JA, Valverde-Monge M, Del Pozo V
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0766
[summary] [PDF full-Text]

Letters to the Editor

Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis
Freemantle N, Piketty C
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0727
[summary] [PDF full-Text]

Is environmental pollen concentration a risk factor for SARS-CoV-2 infection?
Moral de Gregorio AJ, Guzmán Rodríguez R, Senent Sánchez CJ, Lemus Calderón JA, Valero Santiago A
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0743
[summary] [PDF full-Text] [Supplemental Materials]

Referral criteria for asthma and the pandemic: new challenges, new responses
Delgado Romero J, Núñez Palomo S, Uréndez Ruiz AM, Gómez Ruiz F, Hidalgo Requena A, Álvarez Gutiérrez FJ
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0747
[summary] [PDF full-Text]

A reply letter to ´Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis´
Lihang L, Han Y
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0745
[summary] [PDF full-Text]

IgE antibodies to galactose-a-1,3-galactose, an epitope of red meat allergen, cross-react with a novel flounder roe allergen
Chinuki Y, Morita E, Takahashi H
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0754
[summary] [PDF full-Text] [Supplemental Materials]