Ahead of Print


Review

Up-Dosing Antihistamines in Chronic Spontaneous Urticaria: Efficacy and Safety. A Systematic Review of the Literature
Iriarte Sotés P, Armisén M, Usero-Bárcena T, Rodriguez Fernández A, Otero Rivas M, Gonzalez MT, Meijide Calderón A, Veleiro B, Urtigal, the Galician Group of Interest in Urticaria
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0649
[summary] [PDF full-Text]

Clinical Approach to Mast Cell Activation Syndromes: A Practical Overview
Matito A, Escribese MM, Longo N, Mayorga C, Luengo-Sánchez O, Pérez-Gordo M, Matheu V, Labrador-Horrillo M, Pascal M, Seoane-Reula ME, on behalf of the Comité de Inmunología de la Sociedad Española de Alergología e Inmunología Clínica (SEAIC)
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0675
[summary] [PDF full-Text]

Dupilumab: a Review of Present Indications and Uses Out Of Indication
Muñoz-Bellido FJ, Moreno E, Dávila I
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0682
[summary] [PDF full-Text]

Treatment and outcome in deficiency of adenosine deaminase 2: a literature review
Zhang B, Xu N, Chen J, Zhang S, Huang X, Shen M, Zeng X
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0748
[summary] [PDF full-Text] [Supplemental Materials]

Guidelines

Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Quinolones
Doña I, Blanca-López N, Boteanu C, Cueva-Oliver B, Fernández-Sánchez FJ, Gajate P, García-Avilés MC, García-Núñez I, Lobera T, Moreno E, Rojas P, Rosado A
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0669
[summary] [PDF full-Text]

Spanish Society vision of Drug challenge tests
Audicana A, Ortega N, Lobera T, Blanca N, De la Parte B, García I, Gelis S, Martín J, Barranco R, Vila C, Laguna JJ, On behalf of SEAIC Drug Allery Committee
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0681
[summary] [PDF full-Text]

Hypersensitivity Reactions to Cancer Chemotherapy: Practical Recommendations of ARADyAL for Diagnosis and Desensitization
Vega A, Jimenez-Rodriguez TW, Barranco R, Bartra J, Diéguez MC, Doña I, Fernández-Rivas M, Gandolfo-Cano M, Gastaminza-Lasarte G, González-Mancebo E, de la Hoz Caballer B, Sánchez-Morillas L, Torres MJ, Berges-Gimeno MP, Muñoz-Cano R
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0712
[summary] [PDF full-Text]

Original Articles

PAGE Study: Summary of a study protocol to estimate the prevalence of severe asthma in Spain using big-data methods
Almonacid Sánchez C, Melero Moreno C, Quirce Gancedo S, Sánchez-Herrero MG, Álvarez Gutiérrez FJ, Bañas Conejero D, Cardona V, Soriano JB
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0483
[summary] [PDF full-Text]

Low expression of ICAM-1 in blood eosinophils in patients with active eosinophilic esophagitis
Pérez-Lucendo I, Gómez Torrijos E, Donado P, Melero R, Feo-Brito F, Urra JM
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0489
[summary] [PDF full-Text] [Supplemental Materials]

Severe cutaneous adverse reactions (SCARs) to drugs in Latin America: RACGRAD study
Rojas Mejía DV, Zwiener RD, Cardona Villa R, Ramírez LF, Silva Espinosa DL, Zanacchi VA, Piraino Sosa P, Ensina LF, Giavina Bianchi P, Coelho Portilho N, Aun MV, Matos Benavides E, Martínez Ruíz DM, Jares E, Serrano Reyes CD
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0497
[summary] [PDF full-Text]

Nailfold Videocapillaroscopic Findings in Bradykinin-Mediated Angioedema
Cesoni Marcelli A, Loffredo S, Petraroli A, Carucci L, Mormile I, Ferrara AL, Spadaro G, Genovese A, Bova M
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0524
[summary] [PDF full-Text]

Endothelial dysfunction and pentraxin-3 in clinically stable adult asthma patients
Pacholczak R, Kuszmiersz P, Iwaniec T, Zaręba L, Zarychta J, Walocha JA, Dropiński J, Bazan-Socha S
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0563
[summary] [PDF full-Text] [Supplemental Materials]

Airborne food and aeroallergens levels in healthcare settings. An unaccounted but potentially relevant source of exposure?
Leal M, Paciência I, Farraia M, Cavaleiro Rufo J, Castro Mendes F, Delgado L, Viegas C, Moreira A
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0623
[summary] [PDF full-Text] [Supplemental Materials]

Direct costs of Acute Rhinosinusitis in Spain - a prospective and observational study (PROSINUS)
Jaume F, Quintó LL, Alobid I, Mullol J
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0525
[summary] [PDF full-Text]

Factors associated with asthma control in 121 preschool children
Leiria-Pinto P, Carreiro-Martins P, Peralta I, Marques J, Finelli E, Alves C, Belo J, Alves M, Papoila AL, Neuparth N
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0630
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis: a decade of a nationwide allergy society registry
Gaspar A, Santos N, Faria E, Câmara R, Rodrigues-Alves R, Carrapatoso I, Gomes E, Pereira AM, Carneiro-Leão L, Morais-Almeida M, Delgado L, Pedro E, Branco-Ferreira M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0515
[summary] [PDF full-Text]

Molecular Sensitization Profile to Dermatophagoides pteronyssinus Dust Mite in Portugal
Limão R, Spínola Santos A, Araújo L, Cosme J, Inácio F, Tomaz E, Ferrão A, Santos N, Sokolova A, Môrete A, Falcão H, Cunha L, Ferreira A, Bras A, Ribeiro F, Lozoya C, Leiria Pinto P, Prates S, Plácido J, Coimbra A, Taborda-Barata L, Pereira Santos MC, Pereira Barbosa M, Pineda F
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0533
[summary] [PDF full-Text]

Detection of Gibberellin-Regulated Protein (Peamaclein) Sensitization among Italian Cypress Pollen-Sensitized Patients
Asero R, Abbadessa S, Aruanno A, Barilaro G, Barzaghi C, Bignardi D, Bilò MB, Borro M, Bresciani M, Busa M, Buzzulini F, Cavaliere C, Cecchi L, Ciccarelli A, Cortellini G, Cucinelli F, Deleonardi G, Emiliani F, Farsi A, Ferrarini E, Franchini M, Ingrassia A, Lippolis D, Losappio L, Marra AM, Martini M, Masieri S, Mauro M, Mazzolini M, Muratore L, Murzilli F, Nucera E, Pastorello EA, Pinter E, Polillo BR, Pravettoni V, Quercia O, Rizzi A, Russello M, Sacerdoti C, Scala E, Scala G, Scarpa A, Schroeder J, Uasuf GG, Villalta D, Yang B, Mistrello G, Amato S, Lidholm J
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0542
[summary] [PDF full-Text]

MRGPRX2 and Immediate Drug Hypersensitivity: Insights from Cultured Human Mast Cells
Elst J, Sabato V, Faber MA, Bridts CH, Mertens C, Van Houdt M, Van Gasse AL, Hagendorens MM, Van Tendeloo V, Maurer M, Campillo-Davo D, Timmermans JP, Pintelon I, Ebo DG
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0557
[summary] [PDF full-Text] [Supplemental Materials]

Api m 6 and Api m 10 as Major Allergens in Patients with Honeybee Venom Allergy
Vega-Castro A, Rodríguez-Gil D, Martínez-Gomariz M, Gallego R, Peña MI, Palacios R
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0639
[summary] [PDF full-Text] [Supplemental Materials]

Use of Dupilumab for 543 Adult Patients with Moderate-To-Severe Atopic Dermatitis: A Multicenter, Retrospective Study
Nettis E, Ferrucci SM, Ortoncelli M, Pellacani G, Foti C, Di Leo E, Patruno C, Rongioletti F, Argenziano G, Macchia L, Tavecchio S, Napolitano M, Ribero S, Bonzano L, Romita P, Di Bona D, Nisticò SP, Piras V, Calabrese G, Detoraki C, Carbonara M, Fabbrocini G
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0641
[summary] [PDF full-Text]

Clinical and immunologic changes due to subcutaneous immunotherapy with cat and dog extracts using an ultrarush up-dosing phase: a real-life study
Uriarte SA, Grönlund H, Wintersand A, Bronge J, Sastre J
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0656
[summary] [PDF full-Text] [Supplemental Materials]

A Specialized Therapeutic Approach to Chronic Urticaria Patient’s Refractory to H1-Antihistamines Improves the Burden of the Disease. The Spanish AWARE Experience
Gimenez-Arnau A, Bartra J, Ferrer M, Jauregui I, Borbujo J, Figueras I, Muñoz-Bellido FJ, Pedraz J, Serra-Baldrich E, Tejedor-Alonso MA, Velasco M, Terradas P, Labrador M
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0661
[summary] [PDF full-Text] [Supplemental Materials]

Unraveling Kiwifruit Allergy Diagnosis: Usefulness of the Current Diagnostic Tests
D’Amelio CM, Bernad A, García-Figueroa BE, Garrido-Fernández S, Azofra J, Beristain A, Bueno-Díaz C, Garrido-Arandia M, Gastaminza G, Ferrer M, Díaz Perales A, Villalba M, Goikoetxea MJ
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0691
[summary] [PDF full-Text] [Supplemental Materials]

Budget impact analysis of Fractional Exhaled Nitric Oxide Monitoring for the Management of Childhood Asthma: The Colombian National Health System perspective
Buendía JA, Acuña-Cordero R, Rodriguez-Martinez CE
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0690
[summary] [PDF full-Text]

Incidence of Fatal Anaphylaxis: A Systematic Review of Observational Studies
Perez-Codesido S, Rosado-Ingelmo A, Privitera-Torres M, Pérez Fernández E, Nieto-Nieto A, Gonzalez-Moreno A, Grifol-Clar E, Alberti-Masgrau N, Tejedor-Alonso MA
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0693
[summary] [PDF full-Text] [Supplemental Materials]

Onset of nut allergy in a pediatric cohort: clinical and molecular patterns. AFRUSEN study
Ibáñez-Sandin MD, Rodríguez del Río P, Alvarado MI, García BE, Garriga-Baraut T, Reche Frutos M, Escudero C, Ramirez A, Vila L, Lasa EM, Blasco C, Marchán-Martin E, Martorell A, Sanchez-García S, Rodríguez-Álvarez M, Infante S, Rodríguez Vazquez V, Olaguibel JM, Labrador-Horrillo M, Carrillo T, AFRUSEN task force, Pediatric Allergy Committee, Spanish Society of Allergy and Clinical Immunology (SEAIC)
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0696
[summary] [PDF full-Text] [Supplemental Materials]

Risk Factors in Severe Anaphylaxis: Which Matters The Most, Food or Cofactors?
Casas-Saucedo R, de la Cruz C, Araujo-Sánchez G, Gelis S, Jimenez T, Riggioni S, San Bartolomé C, Pascal M, Bartra Tomás J, Muñoz-Cano R
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0698
[summary] [PDF full-Text] [Supplemental Materials]

Allergen Profile of London Plane Tree Pollen: Clinical and Molecular Pattern in Central Spain
Nuñez-Borque E, Betancor D, Fernández-Bravo S, Gómez-Cardeñosa A, Esteban V, Garrido-Arandia M, de las Heras M, Pastor-Vargas C, Cuesta-Herranz J
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0702
[summary] [PDF full-Text]

Seed Storage Proteins, 2S Albumin And 11S Globulin, Associated to Severe Allergic Reactions after Flaxseed Intake
Bueno-Díaz C, Biserni C, Martín-Pedraza L, de las Heras M, Blanco C, Vázquez-Cortés S, Fernández-Rivas M, Batanero E, Cuesta-Herranz J, Villalba M
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0713
[summary] [PDF full-Text] [Supplemental Materials]

Helios negative Regulatory T-cells as a key factor of immune tolerance in non-allergic beekeepers
Ruiz-Leon B, Navas A, Serrano P, Espinazo M, Guler I, Alonso C, Jurado A, Moreno-Aguilar C
J Investig Allergol Clin Immunol 2022; Vol. 32(6)
doi: 10.18176/jiaci.0722
[summary] [PDF full-Text] [Supplemental Materials]

Atopic Dermatitis Patients with Pet Dander Sensitization Mount IgE and T cell Responses to Mammalian Cystatins Including the Human Self-Protein
Roesner LM, Swiontek K, Lentz D, Begemann G, Kienlin P, Hentges F, Ollert M, Werfel T, Hilger C
J Investig Allergol Clin Immunol 2022; Vol. 32(5)
doi: 10.18176/jiaci.0737
[summary] [PDF full-Text] [Supplemental Materials]

Usefulness of the Allergen Specific Nasal Provocation Test in the Diagnosis of Shellfish Allergy
Gelis S, Rueda M, Pascal M, Fernández-Caldas E, Abel Fernández E, Araujo-Sánchez G, Bartra J, Valero A
J Investig Allergol Clin Immunol 2022; Vol. 32(6)
doi: 10.18176/jiaci.0736
[summary] [PDF full-Text] [Supplemental Materials]

Serum microRNAs catalog asthmatic patients by phenotype
Gil-Martínez M, Rodrigo-Muñoz JM, Sastre B, Cañas JA, García-Latorre R, Redondo N, de la Fuente L, Mínguez P, Mahíllo-Fernández I, Sastre J, Quirce S, Caballero ML, Olaguibel JM, Pozo V
J Investig Allergol Clin Immunol 2022; Vol. 32(6)
doi: 10.18176/jiaci.0753
[summary] [PDF full-Text] [Supplemental Materials]

Practitioner’s Corner

Anaphylaxis after the Epicutaneous Application of Argan Oil
de las Marinas Álvarez MD, Martorell Calatayud C, Castillo Fernández M, Alvariño Martín M, Félix Toledo R, Pineda De La Losa F, Cerdá Mir JC, Martorell Aragonés A
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0596
[summary] [PDF full-Text]

Anaphylaxis Induced By Beer
Navarro L, Lazo C, Pineda F, Labrador-Horrillo M, Roger A, Basagaña M
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0643
[summary] [PDF full-Text]

Anaphylactic Shock to a DEET-Containing Insect Repellent
Giangrande N, García-Menaya JM, Vergara-Prieto E, Pineda De La Losa F, Castillo-Fernández M, Cordobés-Durán C, Marcos-Fernández M, Bobadilla-González P
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0644
[summary] [PDF full-Text] [Supplemental Materials]

Cumulative Pollen Concentration Curves for Pollen Allergy Diagnosis
Hoffmann TM, Travaglini A, Brighetti MA, Acar Şahin A, Arasi S, Bregu B, Caeiro E, Caglayan Sozmen S, Charpin D, Delgado L, Dimou M, Fiorilli M, Fonseca JA, Goksel O, Kalpaklioglu F, Lame B, Mazon A, Mesonjesi E, Nieto A, Öztürk A, Pajno G, Papadopoulos NG, Pellegrini E, Pereira AM, Pereira M, Pinar NM, Pinter E, Priftanji A, Sackesen C, Sfika I, Suarez J, Thibaudon M, Tripodi S, Ugus U, Villella V, Matricardi PM, Dramburg S, @IT.2020 study team
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0646
[summary] [PDF full-Text] [Supplemental Materials]

Kounis Syndrome Due to Urapidil
Herrera-Lasso V, Dordal MT, Alonso G, Camprubí I, Lleonart R
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0645
[summary] [PDF full-Text]

Epithelial Permeability to Ole E 1 Is More Dependent on Functional Bronchial Epithelium-State than on Der P 1-Protease Activity That Acts As Adjuvant to the Bystander Allergen
López-Rodríguez JC, González M, Bogas G, Mayorga C, Villalba M, Batanero E
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0603
[summary] [PDF full-Text] [Supplemental Materials]

Efficacy of Benralizumab and Clinical Course of Igg4 on Eosinophilic Granulomatosis with Polyangiitis
Miyata Y, Inoue H, Homma T, Tanaka A, Sagara H
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0648
[summary] [PDF full-Text]

Profilins and Food Dependent Exercise-Induced Anaphylaxis
Gómez Torrijos E, Gratacós Gómez AR, González Jimenez OM, Joyanes Romo B, Palacios Cañas A, García Rodríguez R
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0650
[summary] [PDF full-Text]

Anaphylaxis to Tranexamic Acid: 2 Cases Confirmed by Drug Provocation Test, What about Skin Tests?
El Hanache H, Verdaguer M, Collin L, Babin M, Favrelière S, Vidal Husser S, Maissiat MH, Hoppe A, Morisset M
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0651
[summary] [PDF full-Text]

Un-Sustained Response to Benralizumab in Eosinophilic Asthma with Previous 3 Year Mepolizumab Administration
Kurosawa M, Shimizu Y, Sutoh Y, Sutoh E
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0652
[summary] [PDF full-Text]

Oxaliplatin Allergy is not Always what it Seems. A Case Report
Farzanegan R, Borrás J, Busquier I, Castelló JV, Torres Gorriz MC, Cervera Aznar R, Enrique E
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0655
[summary] [PDF full-Text]

Seasonal administration of omalizumab in patients with uncontrolled asthma and sensitization to olive pollen
Serrano P, Navas A, Ruiz-León B, Herrero L, Rondón C, Jurado A, Moreno-Aguilar C
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0657
[summary] [PDF full-Text] [Supplemental Materials]

Icatibant in Severe Acute Respiratory Syndrome Coronavirus 2: a case description
Pecori D, Della Siega P, Sozio E, Barbano E, Mazzoran L, Zanichelli A, Sbrana F, Federico I, Bassi F, Fabris M, Vendramin I, Sbrojavacca R, Tascini C
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0659
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylactic Shock to Lidocaine: A Rare Case Report with Evaluation of Cross-Reactivity among Local Anesthetics
Barradas Lopes J, Reis Ferreira A, João Sousa M, Cadinha S
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0658
[summary] [PDF full-Text] [Supplemental Materials]

Non-Immediate Hypersensitivity Reaction to Rifaximin Confirmed With a Drug Challenge Test
Moya B, García-Moguel I, Mielgo R, Herráez L, Crespo JF
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0660
[summary] [PDF full-Text]

Cross-Reactivity between Carbonic Anhydrase Inhibitor Confirmed By Lymphocyte Transformation Test: A Case of Methazolamide Induced Toxic-Epidermal Necrolysis
Kyoung-Hee S, Sae-Hoon K, Hye-Ryun K
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0662
[summary] [PDF full-Text]

Impact of Short-Term Exposure to Below Recommended PM10 Pollution Levels on Asthma Exacerbations
Betancourt A, Zapatero A, Pola-Bibian B, Dominguez-Ortega J
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0663
[summary] [PDF full-Text] [Supplemental Materials]

Are The Proton Pump Inhibitor-Responsive And Non-Responsive Phenotypes Of Eosinophilic Esophagitis Exactly The Same?
Gómez Torrijos E, Castro Jimenez A, Gratacós Gómez AR, González Jiménez OM, Joyanes Romo JB, Feo Brito F, Urra Ardanaz JM, García Rodríguez R
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0666
[summary] [PDF full-Text] [Supplemental Materials]

Erythema Multiforme after Risedronate Intake: Cross-Reactivity Study
Garcia-Nunez I, Algaba-Marmol MA, Castro-Cost C
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0668
[summary] [PDF full-Text] [Supplemental Materials]

Efficacy of Mepolizumab Extended Interval Dosing For Two Asthmatic Cases with Chronic Eosinophilic Pneumonia
Sato H, Miyata Y, Inoue H, Tanaka A, Sagara H
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0671
[summary] [PDF full-Text] [Supplemental Materials]

The Burden of Allergens in Surimi Based Products Diminish With Industrial Processing
Pedrosa M, Loli-Ausejo D, Garcia-Lozano JR, Fiandor A, Lluch-Bernal M, Hurtado JL, Dominguez-Ortega J, Quirce S, Gasset M, Rodriguez-Perez R
J Investig Allergol Clin Immunol 2021; Vol. 31(5)
doi: 10.18176/jiaci.0674
[summary] [PDF full-Text] [Supplemental Materials]

Severe Anaphylaxis on Murine Antibodies in Sulesomab
Jacobs J, Coorevits L, Verscuren R, Frans G, Schrijvers R, Breynaert C
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0676
[summary] [PDF full-Text] [Supplemental Materials]

Successful Desensitization to Daratumumab after Severe Life-Threatening Reaction in A Patient with Refractory Multiple Myeloma
Carrón-Herrero A, Solano-Solares E, Rita CG, Rodríguez-Martín E, Berges-Gimeno MP, Ruedas A, Barbolla I
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0678
[summary] [PDF full-Text]

Where Have All The Nasal Polyposis Gone?
Ortega-Martin L, Betancor D, Barroso B, Valverde-Monge M, Santillan J, Villacampa JM, Sastre J
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0679
[summary] [PDF full-Text]

Unusual Secretion of Eosinophil Mediators Induced by Benralizumab
Cañas JA, Valverde-Monge M, Rodríguez-Nieto MJ, González-Mangado N, Sastre J, del Pozo V
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0684
[summary] [PDF full-Text] [Supplemental Materials]

First Case of Symmetric Drug-Related Intertriginous and Flexural Exanthema Induced by Meropenem
Blanco Garcia-Granero D, Barranco R, García-Moguel I, Velasco V, Diéguez Pastor MC
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0685
[summary] [PDF full-Text] [Supplemental Materials]

The Importance of Small Airway Dysfunction in Asthma. The GEMA-FORUM III Task Force
Plaza V, Trigueros JA, Cisneros C, Domínguez-Ortega J, Cimbollek S, Fernández S, Hernández J, López JD, Ojanguren I, Padilla A, Pallarés A, Sánchez-Toril FJ, Torrego A, Urrutia I, Quirce S, GEMAFORUM Task Force
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0686
[summary] [PDF full-Text] [Supplemental Materials]

Neutrophilic Generalized Fixed Drug Eruption Induced By Etoricoxib
Vera A, Freih A, Múgica MV, Vega F, Belver MT, Blanco C
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0687
[summary] [PDF full-Text] [Supplemental Materials]

Large Local Reactions to Hymenoptera Stings Negatively Affect Quality Of Life to the Same Degree as Systemic Reactions
Sánchez-Morillas L, Alfaya Arias T, Martínez San Ireneo M, Domínguez Noche C, Vega Gutierrez JM, Vega Castro A, Moreno Mata E, Marqués L, Fuentes Ferrer M, Ruiz-León B, Hymenoptera Allergy Committee of the SEAIC
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0688
[summary] [PDF full-Text] [Supplemental Materials]

Benralizumab: Blowing Out Eosinophilic Pulmonary Vasculitis in A EGPA Patient
Bormioli S, Vultaggio A, Nencini F, Comin CE, Bercich L, Bezzi M, Vivarelli E, Calosi L, Chiccoli F, Matucci A
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0689
[summary] [PDF full-Text] [Supplemental Materials]

COVID-19 and TEN treated with IVIG and Total plasma exchange. Simultaneous systemic treatment for both diseases
Krajewski A, Mlynska-Krajewska E, Kaczynska K, Strużyna J, Mazurek MJ
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0692
[summary] [PDF full-Text]

Patterns of Cross-Reactivity in Patients with Immediate Hypersensitivity Reactions to Gadobrutol
Gallardo-Higueras A, Moreno EM, Muñoz-Bellido FJ, Laffond ELaffond , Gracia-Bara MT, Macias EM, Campanon MV, de Arriba S, Martin C, Sobrino M, Davila I
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0694
[summary] [PDF full-Text]

Ascites as a Rare Presentation of Eosinophilic Enteritis in a Pollinic Patient
López-Sáez MP, Magdalena Betencourt K, Muñoz Tornero M, Alajarin Cervera M, Serrano Santos E, Sánchez-Guerrero Villajos I, López Sánchez D
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0697
[summary] [PDF full-Text]

Circulating Epithelial Cell Cytokines Are Associated With Early Onset Atopic Dermatitis
Gamez C, Metcalfe J, Prescott SL, Palmer DJ
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0699
[summary] [PDF full-Text] [Supplemental Materials]

Identification of Ribosomal Proteins as Cross-Reactive Allergens in a Case of Mushroom Food Allergy
Ogino R, Chinuki Y, Tobita R, Morita E
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0700
[summary] [PDF full-Text] [Supplemental Materials]

Psychiatric and Clinical Characteristics of Hereditary Angioedema Patients Who Experienced Attacks during COVID-19
Mete Gökmen N, Kuman Tunçel O, Boğatekin G, Bulut G, Demir S, Gelincik A, Tunakan Dalgıç C, Mungan D
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0701
[summary] [PDF full-Text] [Supplemental Materials]

Delayed Reaction to Gadobutrol in a Nurse with Myocarditis After SARS-CoV2 Infection
Gallardo A, Gracia Bara MT, Moreno EM, Laffond E, Muñoz Bellido FJ, Martin C, Sobrino M, Dávila I
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0706
[summary] [PDF full-Text]

Allergic Rhinitis Due To the Ornamental Plant Sansevieria Trifasciata
Nin-Valencia A, Tomás-Pérez M, Bartolomé Zavala B
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0704
[summary] [PDF full-Text]

Immediate Hypersensitivity to Mealworm and Cricket: Beyond Shrimp and House Dust Mite Cross Reactivity
Mankouri F, Sereme Y, Michel M, Piarroux R, Pahus L, Chanez P, Vitte J, Gouitaa M
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0707
[summary] [PDF full-Text] [Supplemental Materials]

Management of Hypersensitivity to Trimethoprim-Sulfamethoxazole with Ultra-Rapid Desensitization Protocol in HIV Infection
Villarreal-Gonzalez RV, Gonzalez-Diaz SN, Canel Paredes A, De Lira-Quezada CE, Rocha-Silva GK, López Méndez A
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0708
[summary] [PDF full-Text]

Acute Localized Exanthematouspustulosis Due to Alendronate
Bautista-Villanueva S, Galleani C, Barranco R, Bellón T, Blanco M, García-Moguel I
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0709
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylaxis to Sunflower Seed with Tolerance to Other Nuts. The Role of Lipophilic Allergens
González-Bravo L, Laiseca-García J, Pineda F, Rosado A
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0710
[summary] [PDF full-Text]

Custard Apple Allergy with Glycosyltransferase as the Allergen Involved
Carrón-Herrero A, Fernández-Lozano C, Peracho L, Martínez-Alonso E, Alcázar A, Martínez-Botas J, de-La-Hoz-Caballer B, González-de-Olano D
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0711
[summary] [PDF full-Text]

Exacerbation Rate Reduction with Mepolizumab, Stratified by Maintenance OCS Use and Eosinophil Levels. A Post-Hoc Analysis of DREAM and MENSA Studies
Bobolea I, Bañas D, Melero C, de Andrés AI, Joksaite S, Sánchez-Herrero G
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0714
[summary] [PDF full-Text]

Anaphylaxis Due to Silene Vulgaris Ingestion
Haroun-Díaz E, Torres I, Blanca-López N, Somoza ML, Martín-Pedraza L, Ruano FJ, Vázquez de la Torre M, Cuesta-Herranz J, Bartolomé Zavala B, Blanca M, Canto Díez G
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0715
[summary] [PDF full-Text]

Consistency of sIgE Determination and Basophil Activation Test in Vespa velutina nigrithorax Allergy
Rodríguez-Vázquez V, Gómez-Rial J, Monsalve RI, Vidal C
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0716
[summary] [PDF full-Text] [Supplemental Materials]

Administration of the Comirnaty® Vaccine in a Fractional Regimen in Two Patients with Immediate Acute Urticaria after the First Dose
Antón Gironés M, Montoro Lacomba j, Navarro Cascales T, Lindo Gutarra M, Marco de la Calle FM
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0717
[summary] [PDF full-Text] [Supplemental Materials]

Hypersensitivity to COVID-19 Vaccine Confirmed by a Positive Skin Test Result: A Case Report
Pérez-Codesido S, Rosado A, Alonso-Díaz-de-Durana MD, Alfaya Arias T, González-Moreno A, Tejedor Alonso MA
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0718
[summary] [PDF full-Text] [Supplemental Materials]

Sugammadex Induced Anaphylaxis: Two Case Reports
Lazo Uslar C, Navarro Vives L, Miquel Marco S, Roger Reig A, Basagaña Torrento M
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0719
[summary] [PDF full-Text]

Immediate-Type Hypersensitivity to Polyethylene Glycol (PEG) Including a PEG-containing COVID-19 Vaccine Revealed by Intradermal Testing
Pickert J, Hennighausen I, Mühlenbein S, Möbs C, Pfützner W
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0720
[summary] [PDF full-Text] [Supplemental Materials]

Kounis syndrome in a Covid-19 patient following intravenous azithromycin administration
Gogos C, Sachpekidis V, Moschovidis V, Styliadis I, Kounis NG
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0723
[summary] [PDF full-Text] [Supplemental Materials]

B cells and COVID-19: Lessons from agammaglobulinemia patients and the study of functional B cell polymorphisms
Speletas M, Raftopoulou S, Farmaki E, Gatselis N, Germanidis G, Mouchtouri V, Hatzianastasiou S, Georgiadou S, Tsinti G, Tsachouridou O, Tseroni M, Metallidis S, Dalekos G, Eibel H, Hadjichristodoulou C
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0726
[summary] [PDF full-Text]

Anaphylaxis to goat’s and sheep’s milk in an adult tolerant to cow milk: A sensitization profile study
Hirsiger JR, Heijnen IAFM, Hartmann K, Berger CT
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0721
[summary] [PDF full-Text] [Supplemental Materials]

Findings in Chest High-Resolution Computed Tomography in Severe Asthma
Extremera Ortega AM, Moreno Lozano L, González Jiménez OM, Borja Segade J, Joyanes Romo JB, Muñoz Rodríguez JR, Feo-Brito F, Galindo Bonilla PA
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0725
[summary] [PDF full-Text] [Supplemental Materials]

Caution against Temporary Tolerance and Negative Skin Testing During Anergic Period Following Systemic Reactions
Li P, Chiang V, Yeung HHF, Au EYL
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0724
[summary] [PDF full-Text]

DRESS Syndrome: Patch Testing As a Diagnostic Method That Brings Us Closer to a Certain Result
García-Paz V, González-Rivas M, Otero-Alonso A
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0728
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylactic Reactions with Three Non-Related Drugs (Gadoteridol, Paclitaxel, Bevacizumab) In a Patient with Severe Comorbidities
González-Bravo L, Laiseca García J, Alonso-Díaz-de-Durana MD, Nieto Nieto A, Álvarez-Twose I, Tejedor Alonso MA, Alfaya Arias T
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0729
[summary] [PDF full-Text]

Severe Perioperative Anaphylaxis Due to Allergy to the Sugammadex-Rocuronium Complex
Lopez-Raigada A, Vega de la Osada F, Lopez-Sanz C, Múgica García MV, Alfranca A, Blanco C
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0730
[summary] [PDF full-Text] [Supplemental Materials]

Polyethylene glycol allergy and immediate-type hypersensivitity reaction to COVID-19 vaccination: case report
Habran M, Vandebotermet M, Schrijvers R
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0740
[summary] [PDF full-Text] [Supplemental Materials]

Salt-dependent aquagenic urticaria, challenge test and histological features. Case report
Laiseca García J, Gónzalez Bravo L, Gomez de la Fuente E, Tristán Martin B, Sarró Fuentes C, Rosado A
J Investig Allergol Clin Immunol 2022; Vol. 32(2)
doi: 10.18176/jiaci.0735
[summary] [PDF full-Text]

Drug hypersensitivity in cutaneous manifestations of SARS-CoV-2 infected patients
Solano-Solares E, Chica-Guzmán V, Pérez-Allegue I, Cabrera-Hernández R, Fernández-Guarino M, Fernández-Nieto D, de-la-Hoz-Caballer B, González-de-Olano D, García-Bermejo L, de-Andres-Martin A, Moreno-García-del-Real C
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0744
[summary] [PDF full-Text] [Supplemental Materials]

Allergic reactions after administration of pfizer-biontech covid-19 vaccine to healthcare workers at a tertiary hospital
Loli-Ausejo D, González de Abreu JM, Fiandor A, Cabañas R, Domínguez-Ortega J, Caballero ML, Lluch-Bernal M, Rodrigo García-Panto C, Núñez MC, Quirce S
J Investig Allergol Clin Immunol 2022; Vol. 31(6)
doi: 10.18176/jiaci.0751
[summary] [PDF full-Text] [Supplemental Materials]

Anaphylactic shock to Mediterranean silverside (Atherinaboyeri) caused by non-parvalbumin allergens
Giangrande N, García-Menaya JM, Bartolomé B, Fernández-Bolívar A, Cordobés-Durán C, Dotor-Lavado M, Marcos-Fernández M, Bobadilla-González P
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0732
[summary] [PDF full-Text]

Non-Immediate Maculopapular Erythema To Gadolinium-Based Contrast Agent
Gauthier A, Mankouri F, Demoly P, Chiriac AM
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0733
[summary] [PDF full-Text]

Anaphylactic shock following cataract surgery: a documented intracameral cefuroxime allergy
Mahiat C, Robaye S, Levecq L, Dumesnil D, Sohy C
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0741
[summary] [PDF full-Text]

Exploring adherence to treatment in nasal polyposis
Valverde-Monge M, Barroso B, Ortega-Martin L, Betancor D, Santillan J, Villacampa JM, Sastre J
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0752
[summary] [PDF full-Text]

Contact dermatitis from the glucose sensors: more than isobornyl acrylate (IBOA) allergy
Joyanes Romo JB, Borja Segade JM, Moreno Lozano L, García Rodríguez R, González Jiménez OM, Palacios Cañas A, Meneses Sotomayor JV, Gómez Torrijos E
J Investig Allergol Clin Immunol 2022; Vol. 32(3)
doi: 10.18176/jiaci.0739
[summary] [PDF full-Text]

Immunoglobulin gas milk allergen
Saura Foix MP, Bartolomé B, Barrena Crespo J, Delavalle B, Izquierdo Domínguez A, Hernández Arauzo N, Castillo Marchuet MJ, Viñas Domingo M
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0746
[summary] [PDF full-Text]

Pulmonary Geotrichosis in Chronic Granulomatous Disease
Palacios-Reyes D, Yamazaki-Nakashimada MA, Castaño-Jaramillo L, Roman-Montes CM, González-Lara MF, Scheffler-Mendoza S, Costta-Michuy A, Bustamante J, Blancas-Galicia L
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0749
[summary] [PDF full-Text] [Supplemental Materials]

Recurrent Salmonella Infections and Nephritis Complicating IgA Vasculitis in a Patient with IL12-RB1 Deficiency
Blancas-Galicia L, Peñafiel-Vicuña AK, Scheffler-Mendoza S, Rojas-Maruri M, Rivas-Larrauri F, Rodríguez-Lozano AL, Bustamante J, Yamazaki-Nakashimada MA
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0750
[summary] [PDF full-Text] [Supplemental Materials]

Sensitization profile to related animal proteins (crocodile, frog, and chicken) among fish-allergic patients
Haroun-Díaz E, Blanca-López N, Martín-Pedraza L, Ruano FJ, Somoza ML, Vázquez de la Torre M, Pérez-Alzate D, López-González P, Prieto-Moreno A, Bartolomé B, Blanca M, Canto G
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0705
[summary] [PDF full-Text] [Supplemental Materials]

Letters to the Editor

Eosinophil Count in Induced Sputum Could Be More Sensitive Than In Peripheral Blood to Phenotype Patients with Severe Eosinophilic Asthma
Caballero ML, Dominguez-Ortega J, Nin-Valencia AR, Sánchez-Ocando H, Barranco P
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0647
[summary] [PDF full-Text]

Prevalence and influence of COVID19 in asthma control and lung function in severe asthma patients under biological treatment
Díaz-Campos RM, García-Moguel I, Pina-Maiquez I, Fernández-Rodríguez C, Melero-Moreno C
J Investig Allergol Clin Immunol 2021; Vol. 31(4)
doi: 10.18176/jiaci.0695
[summary] [PDF full-Text]

Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis
Freemantle N, Piketty C
J Investig Allergol Clin Immunol 2021; Vol. 31(6)
doi: 10.18176/jiaci.0727
[summary] [PDF full-Text]

Is environmental pollen concentration a risk factor for SARS-CoV-2 infection?
Moral de Gregorio AJ, Guzmán Rodríguez R, Senent Sánchez CJ, Lemus Calderón JA, Valero Santiago A
J Investig Allergol Clin Immunol 2022; Vol. 32(1)
doi: 10.18176/jiaci.0743
[summary] [PDF full-Text] [Supplemental Materials]

Referral criteria for asthma and the pandemic: new challenges, new responses
Delgado Romero J, Núñez Palomo S, Uréndez Ruiz AM, Gómez Ruiz F, Hidalgo Requena A, Álvarez Gutiérrez FJ
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0747
[summary] [PDF full-Text]

A reply letter to ´Efficacy and Safety of Nemolizumab for Treatment of Adult Atopic Dermatitis´
Lihang L, Han Y
J Investig Allergol Clin Immunol 2022; Vol. 32(4)
doi: 10.18176/jiaci.0745
[summary] [PDF full-Text]