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Case Report |
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Selective Allergy to Lobster in a
Case of Primary Sensitization to House Dust Mites |
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A Iparraguirre,1 R
Rodríguez-Pérez,2 S Juste,1 A
Ledesma,3 I Moneo,2 ML Caballero2 |
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1Department of Allergology, Hospital
General Yagüe, Burgos, Spain
2Department of Immunology, Hospital Carlos III, Madrid,
Spain
3Department of Development, ALK-Abelló, Madrid, Spain
The first 2 authors have contributed equally to this
article. |
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J Investig Allergol Clin Immunol
2009; Vol. 19(5): 409-413 |
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Abstract |
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Allergy to only 1
kind of seafood is
uncommon. We report
a case of selective
allergy to lobster.
We studied a
30-year-old man who
suffered generalized
urticaria, facial
erythema, and
pharyngeal pruritus
after eating
lobster. He had a
more than 10-year
history of mild
persistent asthma
and sensitization to
house dust mites.
The study was
performed by skin
prick test, and
prick-prick test,
oral food challenge,
specific
immunoglobulin (Ig)
E determinations by
CAP (Phadia,
Uppsala, Sweden) and
ADVIA-Centaur
(ALK-Abelló, Madrid,
Spain), and
IgE-immunoblotting.
The patient’s serum
recognized 2
allergens of around
198 kDa and 2
allergens of around
65 kDa from the
lobster extract,
allergens of around
15, 90, and 120 kDa
from
Dermatophagoides
pteronyssinus
extract, and
allergens of around
15 and 65 kDa from
Dermatophagoides
farinae extract.
Serum did not
recognize purified
shrimp tropomyosin.
Immunoblot-inhibition
assay results
indicated
cross-reactivity
between lobster and
mite allergens.
This is the first
report of selective
allergy to lobster.
Key words:
Allergy.
Immunoblotting.
Lobster. House dust
mites. Seafood
allergy.
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